The use of antibiotics in agriculture is fuelling drug resistance and must be cut back or even banned where they are important for humans, The Guardian reports that a study has warned. The Review on Antimicrobial Resistance said global use of antimicrobials in food production at least matched that by humans, extending even to the widespread application in some areas of “last resort” antibiotics for humans – which cannot be replaced when ineffective – to animals.
Just as rising levels of human use of antibiotics are leading to growing resistance, the same is happening in agriculture, the review said in its latest paper. It acknowledges that the proper use of antibiotics is essential for treating infections in animals, as in humans, and offers considerable benefits for food production. But the authors say that “excessive and inappropriate” deployment, including to stop development of infections within a flock or herd, or simply to increase the pace at which animals gain weight, is a problem.
The report quotes Jim O’Neill, the economist and former chair of Goldman Sachs Asset Management who is chairing the review, as saying: “I find it staggering that in many countries, most of the consumption of antibiotics is in animals rather than humans. This creates a big resistance risk for everyone, which was highlighted by the recent Chinese finding of resistance to colistin, an important last-resort antibiotic that has been used extensively in animals.
“As we’ve highlighted, most of the scientific research provides evidence to support curtailing antibiotic use in agriculture. It’s time for policymakers to act on this. We need to radically reduce global use of antibiotics, and to do this we need world leaders to agree to an ambitious target to lower levels, along with restricting the use of antibiotics important to humans.”
The report says the panel of experts undertook a review of 139 academic studies on antibiotic use in agriculture and found that only seven argued found no link between consumption in animals and resistance in humans, while 100 found evidence of a link. They argue therefore that there should be a limit for each country to reduce antibiotic use in food production to an agreed level per kilogram of livestock and fish.
They say this should be determined by experts, but suggest that a good starting point would be reducing levels to that of Denmark – an average of less than 50mg of antibiotics per year per kilogram of livestock in the country.
The review says that “countries need to come together and agree to restrict, or even ban, the use of antibiotics in animals that are important for humans”. The experts also raise concerns over pollution during the manufacture of antimicrobials for human or veterinary use through waste products being discharged into water courses, a process it says could carry “a particular risk for resistance, because the concentrations of antimicrobials found in such scenarios can be many thousands, or even millions, of times higher than at sewage sites, for example”.