Endocrinology
Stringent diet puts diabetes into remission and cuts need for BP medication
June 2nd, 2021 Achieving and maintaining substantial weight loss allowed 8 out of 10 people remission from type 2 diabetes, as well as lowering blood pressure and reducing the need for anti-hypertensive medications, found the Diabetes Remission Clinical Trial...
New drug weekly as safe and efficacious as insulin daily — NRI diabetes trial
March 31st, 2021 A new once-weekly basal insulin injection demonstrated similar efficacy and safety and a lower rate of low blood sugar episodes compared with a daily basal insulin, according to a phase 2 clinical trial. The study results, presented at ENDO 2021,...Maintenance semaglutide injections led to continued weight loss — STEP 4
Sticking with weekly semaglutide injections resulted in continued weight loss for adults with overweight and obesity, according to the Semaglutide Treatment Effect in People with Obesity (STEP) 4 study. MedPage Today reports Dr Domenica Rubino,...
STEP 2 trial: Semaglutide hope for patients with type 2 diabetes
March 10th, 2021 Type 2 diabetes patients treated with the new drug Semaglutide achieved an average weight loss of nearly 10kg and a significant improvement in blood glucose control, according to the STEP 2 multi-centre trial. Last month, STEP 1 reported that more...Obesity contributes to up to half of new diabetes cases annually in the US
Reducing the prevalence of obesity may prevent up to half of new type 2 diabetes cases in the US, according to data from used information from the Multi-Ethnic Study of Atherosclerosis and four cycles of the National Health and Nutrition...
Metabolic surgery versus conventional therapy for type 2 diabetes — 10-year trial
February 3rd, 2021 A 10-year UK-Italian randomised clinical trial, published in The Lancet, showed that metabolic surgery is more effective than medications and lifestyle interventions in the long-term control of severe type 2 diabetes. The study also shows that...
Study contradicts earlier findings on saccharin-for-sugar substitution and diabetes
January 20th, 2021 For those trying to live a healthy lifestyle, the choice between sugar and artificial sweeteners such as saccharin can be confusing. A new study led by researchers at The Ohio State University Wexner Medical Centre and The Ohio State University...
Novel weekly dose of insulin as effective as daily for type 2 diabetes
December 2nd, 2020 A phase 2 trial reported in the New England Journal of Medicine found that a once-a-week insulin injection called icodec led to a similar reduction in blood sugar levels taking insulin daily and had a similar safety profile to daily insulin...
A few kilograms' weight loss nearly halves the risk of diabetes — large UK clinical trial
November 18th, 2020 Losing a few kilograms in weight almost halves people’s risk of developing Type 2 diabetes – according to a large scale research study led by the Norfolk and Norwich University Hospital and the University of East Anglia, published in JAMA...
Additive effects of green tea and coffee on mortality risk in type 2 diabetes patients
October 28th, 2020 Green tea and coffee consumption is linked to a lower risk of dying from any cause among people with type 2 diabetes, suggests a Japanese observational study in The BMJ. Drinking 4 or more daily cups of green tea plus 2 or more of coffee was...Pre-bariatric surgery diet, not bypass, explains metabolic effect
A Swedish study of individuals who underwent a six-week low-calorie diet followed by a bariatric operation found that improvements in several health markers were an effect not of the operation but actually due to the diet. In many studies,...Cinnamon may improve blood sugar control in pre-diabetics — Clinical trial
In individuals with prediabetes, 12 weeks of cinnamon supplementation improved blood sugar control, found a small, randomised international clinical trial. The study, by researchers at Kyung Hee University in Seoul, the Joslin Diabetes...
Obesity increases type 2 diabetes risk six-fold, regardless of genetics
April 29th, 2020 Obesity increases the risk of developing type 2 diabetes by at least 6 times, regardless of genetic predisposition to the disease, concludes research. The study is by Dr Theresia Schnurr and Hermina Jakupovi, Novo Nordisk Foundation Centre for...Evaluating grip strength as a screening tool to identify risk of early diabetes
Muscular weakness is known to be associated with type 2 diabetes mellitus (T2DM) in otherwise seemingly healthy adults, however previous research had not found a way to assess this reliably. The current study was able to identify consistent grip...Fat mass index, not BMI, associated with CVD events in people with diabetes
In people with diabetes, fat mass index, not body mass index (BMI), is associated with a higher risk of cardiovascular events, according to data drawn from the ACCORD randomised controlled trial in the US. Heart disease is a major cause of...