Study disputes effectiveness of anticoagulant drug

Organisation: Position: Deadline Date: Location:

[b]Bivalirudin[/b], a newer anticoagulant, has been touted as being as effective as generic heparin as an options for patients undergoing coronary stenting for ischemic heart disease, but with nearly half the rate of bleeding. However, [s]Science Newsline[/s] reports that several studies have hinted that, compared with heparin, bivalirudin-based regimens might not protect as well against recurrent heart attacks and might increase the risk of stents clotting off. Researchers from [b]Brigham and Women’s Hospital[/b] analysed all of the previous trials to date and found that, compared with heparin-based regimens, bivalirudin-based regimens increased the risk of heart attack and stent thrombosis. Bivalirudin-based regimens decreased the risk of bleeding, but by how much depended on whether other blood thinners were used more with heparin than with bivalirudin.

Full Science Newsline report
The Lancet article summary


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