Friday, 29 March, 2024
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Two proteins needed to stimulate Metadherin gene

A study led by [b]Princeton University[/b] researchers has revealed that the gene Metadherin – which is implicated in promoting the spread of breast cancer tumours – only stimulates tumour growth when the protein made by the gene interacts with a second protein known as SND1. [s]Health Canal[/s] reports that researchers note that Metadherin also plays a role in the initial growth of tumours, which occurs much earlier than the gene’s role in metastasis of the cancer to other parts of the body. ‘This is one of the first examples of a gene playing crucial roles in both the early and late steps of breast cancer progression, said senior corresponding author Yibin Kang, Princeton’s [b]Warner-Lambert/Parke-Davis[/b] Professor of Molecular B Biology. ‘If we can find a molecule to block the function of Metathedrin and reverse the process, this could have a broad impact on many types of cancer.’

[link url=http://www.healthcanal.com/alternative-therapies/52482-diabolical-duo-known-breast-cancer-gene-needs-a-partner-to-initiate-and-spread-tumors.html]Full Health Canal report[/link]
[link url=http://www.cell.com/cancer-cell/abstract/S1535-6108(14)00190-1]Cancer Cell article summary[/link]

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