Coating destroys coronavirus on surfaces for almost 2 weeks

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A Virginia Tech chemical engineer has developed a coating that when painted on common objects inactivates SARS-CoV-2 within minutes and lasts for almost two weeks.

Door knobs, light switches, shopping carts. Fear runs rampant nowadays when it comes to touching common surfaces because of the rapid spread of the coronavirus.

Prof William Ducker, a chemical engineering professor, said, “The idea is when the droplets land on a solid object, the virus within the droplets will be inactivated,” Ducker said.

Since mid-April, Ducker has been working with Leo Poon, a professor and researcher at the University of Hong Kong School of Public Health, to test the film’s success at inactivating the virus. The results of the tests have been outstanding, Ducker said. When the coating is painted on glass or stainless steel, the amount of virus is reduced by 99.9 percent in one hour, compared to the uncoated sample.

“One hour is the shortest period that we have tested so far, and tests at shorter periods are ongoing,” Ducker said.

His expectation is that his team can inactivate the virus in minutes. Results have shown that the coating is robust. It does not peel off after being slashed with a razor blade. It also retains its ability to inactivate the virus after multiple rounds of being exposed to the SARS-CoV-2 virus and then disinfection or after being submerged in water for a week, based on the tests.

If the project’s success continues, it is a significant discovery in fighting the virus’ spread. “Everybody is worried about touching objects that may have the coronavirus,” said Ducker, who recalled that his wife, in March, questioned whether she should sit on a park bench during the pandemic. “It would help people to relax a little bit.”

Already, Ducker’s research was focused on making films that kill bacteria. As the COVID-19 virus began to spread to the US a few months ago, Ducker asked himself “Why not make a coating that can eradicate a virus, rather than bacteria?” “We have to use our chemical knowledge and experience of other viruses to guess what would kill it (SARS-CoV-2),” Ducker said.

Virginia Tech granted essential personnel status to Ducker, his two PhD chemical engineering graduate students – Saeed Behzadinasab and Mohsen Hosseini – and Xu Feng from the university’s department of chemistry so that they could enter campus labs to make the film and test its properties.

“It was an interesting experience,” Ducker said. “Almost the entire campus was shut down, and we were like ghosts wandering the empty halls of Goodwin Hall. But it was very exciting to have such a clear goal. I know that it was a difficult time for many people who were bored, unhappy, or scared. We were just focused on making a coating.”

Next, he needed to find someone who could test the coating’s effectiveness. Through an internet search, Ducker found Poon, who is known for his work studying SARs-CoV-1, which was the virus that caused the SARS outbreak in 2003 and 2004. Poon has been active in the fight against SARS-CoV-2.

For Poon’s tests, Ducker and the graduate students spread three different kinds of coatings on glass and stainless steel. Then, they shipped the samples to Poon. Now, Ducker said he hopes to attract funding in order to mass produce the film. To be sure, the film doesn’t replace other safety measures that people should take to stop the spread of the coronavirus, such as handwashing, physical distancing, and wearing a mask.

Even so, “people won’t have to worry as much about touching objects,” Ducker said. “It will be both practical and reducing fear.”

Abstract
SARS-CoV-2, the virus that causes the disease COVID-19, remains viable on solids for periods of up to one week, so one potential route for human infection is via exposure to an infectious dose from a solid. We have fabricated and tested a coating that is designed to reduce the longevity of SARS-CoV-2 on solids. The coating consists of cuprous oxide (Cu2O) particles bound with polyurethane. After one hour on coated glass or stainless steel, the viral titer was reduced by about 99.9% on average compared to the uncoated sample. An advantage of a polyurethane-based coating is that polyurethane is already used to coat a large number of everyday objects. Our coating adheres well to glass and stainless steel, as well as everyday items that people may fear to touch during a pandemic, such as a doorknob, a pen, and a credit card keypad button. The coating performs well in the cross-hatch durability test and remains intact and active after 13 days immersed in water, or after exposure to multiple cycles of exposure to virus and disinfection.

Authors
Saeed Behzadinasab, Alex Chin, Mohsen Hosseini, Leo LM Poon, William A Ducker

 

Virginia Tech material

 

ACS Applied Materials & Interfaces abstract

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