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FOCUS: THIS WEEK'S TOP STORIES

November 7th, 2018 Body Mass Index (BMI), a measure of body fat, is linked to risk of death from every major cause except transport accidents, according to an analysis of 3.6m people in The Lancet. Overall, both low and high BMI were associated with an increased risk...

CPD-ACCREDITED HIV COURSE

Free CPD-accredited online HIV Course

The BetterCare Adult HIV book most recently updated in 2018, is a comprehensive introduction to the management of adults living with HIV. Developed and maintained by doctors and nurses with extensive experience in the care of adults living with HIV,... November 7th, 2018

WEEKLY ROUNDUP

HIV/AIDS

The Miami monkey 'cured' with two antibodies

A “functional cure” of HIV has been achieved in one monkey given gene therapy that induced it to make two broadly neutralising antibodies against the virus. Researcher José Martinez-Navio of the University of Miami told the HIV Research for... November 7th, 2018

Mental health affects every stage of HIV diagnosis and treatment

HIV clinicians need to be aware that mental health affects every stage of HIV diagnosis and treatment, and manage issues just as they would any other comorbid condition, MedPageToday reports experts say. The prevalence of mental health issues,... November 7th, 2018

Cameroon trial on on dolutegravir versus efavirenz

Dolutegravir-based treatment was no more effective than treatment based on a 400mg dose of efavirenz, a randomised trial conducted in Cameroon has found. However, almost half of people with very high viral loads taking either regimen had a... November 7th, 2018

Two-drug protease inhibitor as effective as three-drug treatment

Antiretroviral treatment with a boosted protease inhibitor and one other drug is just as effective as three-drug antiretroviral therapy containing a boosted protease inhibitor but results in fewer treatment discontinuations due to side-effects, a... November 7th, 2018

Bictegravir matches dolutegravir in first line treatment

A triple combination containing the new integrase inhibitor bictegravir proved just as effective as a dolutegravir-based combination in suppressing viral load over 96 weeks, but people taking bictegravir experienced significantly fewer adverse... November 7th, 2018

Beyond Truvada, what is the future of PrEP?

The recent HIV Research for Prevention conference (HIVR4P 2018) in Madrid reviewed the current menu of agents and novel delivery modalities in development for systemic delivery of pre-exposure prophylactics (PrEP). Oral pre-exposure prophylaxis... November 7th, 2018

INFECTIOUS DISEASES

Diagnostic platform screens for all known human pathogenic bacteria

Scientists at the Centre for Infection and Immunity (CII) in the Columbia University Mailman School of Public Health have developed the first diagnostic platform that can simultaneously screen for all known human pathogenic bacteria as well as... November 7th, 2018

NEUROLOGY

Erenumab an option for patients with difficult-to-treat migraine

"Erenumab might be an option for patients with difficult-to-treat migraine who have high unmet needs and few treatment options," MDLinx reports that Dr Uwe Reuter of Charite Universitaetsmedizin Berlin in Germany and colleagues conclude. Current... November 7th, 2018

ONCOLOGY

Cervical cancer survival rates determined by race in SA

A study has found that black women in South Africa are almost six times more likely to die of cervical cancer than white women and that the five-year survival rates of black and coloured women (40-50%) were significantly worse than those of white... November 7th, 2018

PAEDIATRICS

Children have 2.5 years to establish healthy gut bacteria

A child has until the age of two-and-a-half to establish healthy gut bacteria – with little change after this point, research has revealed. The study also reinforced the important role breastfeeding plays in providing good gut bacteria to babies... November 7th, 2018

PSYCHOLOGY

Free, new reasoning test to challenge the widely used APM

A team of psychologists at the University of California has now developed a free test to measure reasoning ability in undergraduates that takes roughly 10 minutes to complete and is 'highly, comparable' to the widely used Raven's Advanced... November 7th, 2018

PUBLIC HEALTH

SPORT & EXERCISE MEDICINE

Barefoot SA children have better balance but may suffer later

South African children – who usually do not wear shoes during physical activity – have better balance and can jump farther than their German counterparts who are almost always shod, Business Insider reports a pathfinder study has found. But the... November 7th, 2018

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