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Effects of avocados on metabolic syndrome

A systematic review assesses the beneficial effects of the peel, seed, flesh, and leaves of avocados on different components of metabolic syndrome, which is a clustering of risk factors including high blood sugar, cholesterol, blood pressure, and body mass index.

These risk factors lead to an increased risk of type 2 diabetes and cardiovascular disease.

According to studies reported in the literature, avocados have the most beneficial effects on lipid profiles, with changes to LDL-cholesterol, HDL-cholesterol, triglycerides, total cholesterol, and phospholipids.

The peel, seed, flesh, and leaves of avocados have differing effects on components of metabolic syndrome.

"Avocado is a well-known source of carotenoids, minerals, phenolics, vitamins, and fatty acids," wrote the researchers led by Hossein Hosseinzadeh at the Pharmaceutical Research Centre, department of pharmacodynamics and toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. "The lipid- lowering, antihypertensive, antidiabetic, anti-obesity, antithrombotic, anti-atherosclerotic, and cardioprotective effects of avocado have been demonstrated in several studies."

Abstract

Metabolic syndrome (MetS) is a clustering of risk factors including high blood glucose, dyslipidemia, hypertension, and obesity that lead to the increased risk of type 2 diabetes mellitus and cardiovascular diseases (CVDs), which are among leading causes of death in the world. Metabolic syndrome increases the risk of type 2 diabetes mellitus and CVDs by approximately five and three folds, respectively. Therefore, it is of vital importance to manage such conditions with herbal options which have less undesirable adverse effects and may be more efficacious in comparison with synthetic options. Avocado is a well-known source of carotenoids, minerals, phenolics, vitamins, and fatty acids. The lipid-lowering, antihypertensive, antidiabetic, anti-obesity, antithrombotic, antiatherosclerotic, and cardioprotective effects of avocado have been demonstrated in several studies. In this review, we aimed to find out avocado's pharmacological effects on different components of MetS. Moreover, this review report is performed on the MetS effects of peel, seed, flesh, and leaves of avocado.

Authors
Jamshid Tabeshpour, Bibi Marjan Razavi, Hossein Hosseinzadeh

[link url="https://www.sciencedaily.com/releases/2017/04/170410110730.htm"]Wiley material[/link]
[link url="http://onlinelibrary.wiley.com/doi/10.1002/ptr.5805/abstract;jsessionid=C07FE12F3CE2CDD4468A95760B425C9C.f02t01?systemMessage=Pay+Per+View+on+Wiley+Online+Library+will+be+unavailable+on+Saturday+15th+April+from+12%3A00-09%3A00+EDT+for+essential+maintenance.++Apologies+for+the+inconvenience."]Phytotherapy Research abstract[/link]

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