Sunday, 3 March, 2024
HomeOncologyChemo or radiation could see some cancer cells dodging death

Chemo or radiation could see some cancer cells dodging death

Under stress from chemotherapy or radiation, some cancer cells dodge death by consuming a bit of themselves, allowing them to essentially sleep through treatment and later awaken as tougher, resistant disease. [s]Health Canal[/s] reports that researchers at the [b]University of Texas MD Anderson Cancer Centre[/b], publishing in [s]Cell[/s], found that interfering with a single cancer-promoting protein and its receptor can turn this resistance mechanism into lethal, runaway self-cannibalisation. 'Prolactin is a potent growth factor for many types of cancers, including ovarian cancer,' said senior author prof Anil Sood. 'When we block prolactin signalling, it sets off a chain of downstream events that result in cell death by autophagy.' 'Our findings provide a clinical rationale for blocking prolactin and its receptor and for using prolong autophagy as an alternative strategy for treating cancers,' said Yunfei Wen, instructor of Gynaecologic Oncology.

[link url=]Full Health Canal report [/link]
[link url=]Cell full study[/link]

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