A team of scientists at the [b]Gladstone Institutes[/b] has identified a new way to make latent HIV reveal itself, which could help overcome one of the biggest obstacles to finding a cure for HIV infection, says a [s]News-Medical[/s] report. They discovered that increasing the random activity, or noise, associated with HIV gene expression – without increasing the average level of gene expression – can reactivate latent HIV. ‘Understanding how to reactivate latent HIV is one of the major challenges we must overcome in order to find a cure for HIV,’ said Leor Weinberger, associate investigator in the [b]Gladstone Institute of Virology and Immunology[/b] and senior author of the study. Roy Dar, the lead author, added, ‘if we can make the virus show itself, we can then use ARVs to eliminate it.’
[link url=http://www.news-medical.net/news/20140606/Scientists-identify-new-way-to-reactivate-latent-HIV.aspx]Full News-Medical report[/link]
[link url=http://www.sciencemag.org/content/early/2014/06/04/science.1250220.abstract?sid=8557df1d-ebeb-42c6-bf20-42e65ff6e4bb]Science abstract[/link]