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Johnson & Johnson and global partners halt HIV vaccine clinical trial

The primary analysis of Johnson & Johnson's Phase 2b HIV vaccine clinical trial known as the Imbokodo study has been stopped, after showing that...

Fear of side-effects the greatest barrier to long-acting injectable PrEP

Fear of potential severe side effects may be the greatest barrier to long-acting injectable HIV prevention among men who have sex with men (MSM),...

An affordable, optimal second-line HIV treatment now available for low- and middle-income countries

Global health agency Unitaid and the Clinton Health Access Initiative (CHAI) have announced in a statement a groundbreaking pricing agreement with pharmaceutical company Hetero...

COVID-19 not a risk factor for moderate HIV-positive patients — SA study

HIV is not a risk factor for moderate or severe COVID-19 disease, neither is it a risk factor for mortality, found a South Africaa...

England on track to achieve elimination of HIV transmission by 2030

The annual number of new HIV infections among men who have sex with men in England is likely to have fallen dramatically, from 2,770...

High rates of cervical cancer found in women living with HIV

Spotlight reports that a study recently published in The Lancet medical journal found that women living with HIV made up an estimated 63.4% of...

A blood test to find those at high risk of TB in people living with HIV

Researchers from the South African Tuberculosis Vaccine Initiative at the University of Cape Town, the Aurum Institute, the Centre for the AIDS Programme of...

Lenacapavir demonstrates efficacy in people with highly resistant HIV

Lenacapavir, an experimental HIV capsid inhibitor, led to rapid viral load reduction in highly treatment-experienced people with multidrug-resistant virus, according to a study presented...

A rapid review of CROI 2021 Virtual

Dr Paul Sax, a contributing editor at the NEJM Journal Watch Infectious Diseases writes: For a few years in the early 2010s, the Conference on...

Significant increase in taking HIV meds using home delivery model in SA

Home delivery of HIV medicines in South Africa significantly increased viral suppression compared to those who received clinical care, according to a study by...

Anglo American's extraordinary success in combating HIV/Aids

Mining giant Anglo American has done what much of the country, NGOs and the government cannot – persuade men to test for HIV and...

HIV self-test boosts testing awareness among MSM

Distribution of free HIV self-tests via the internet can increase testing for the disease by men who have sex with men (MSM) and boost...

Depression puts SA girls at higher risk of contracting HIV

Teen girls in South Africa face an extraordinary threat of HIV: By the time they reach adulthood, one in four South African girls will...

Tenofovir does not increase risk of kidney disease in those at low risk

Antiretroviral treatment containing the older formulation of tenofovir (TDF) did not increase the risk of chronic kidney disease in previously untreated people with HIV...

Options for two-drug simplification expand but note of caution sounded

Further evidence on the efficacy of two-drug antiretroviral regimens as simplification options for people with suppressed viral load on three-drug regimens was presented last...

96-week results of DISCOVER PrEP trial

The 96-week results of the DISCOVER trial, which compared the efficacy and safety of two different formulations of the antiretroviral drug tenofovir when used...

Dolutegravir and raltegravir cause changes to fat cells

The integrase inhibitors dolutegravir (Tivicay, also in Triumeq and Dovato) and raltegravir (Isentress) cause changes in the structure of fat cells that may promote...

Weight gain after switching to integrase inhibitor treatment is small in Dutch and Swiss cohorts

People with suppressed viral load who switched to an integrase inhibitor-based regimen experienced only small gains in weight and do not appear to gain...

Weight gain after starting ARVs linked to specific drugs

Weight gain after starting antiretroviral treatment probably has multiple causes but appears strongly linked to specific drugs, and to combinations of drugs, Dr Andrew...

Syringe exchange programmes prevented thousands of new HIV cases

Syringe exchange programmes established in Philadelphia and Baltimore prevented a total of 12,483 new cases of HIV over a 10-year period, according to a...

Hair study strengthens link between food insecurity, ART non-adherence

Among women living with HIV, study findings showed that food insecurity was associated with lower antiretroviral treatment (ART) concentrations in hair, suggesting that it...

Telemedicine useful for HIV treatment

Telemedicine, which involves consultation of patients by doctors remotely, is being used in many parts of India. A study has shown that it can...

Routine screening cuts incidence of anal cancer among people living with HIV

A routine anal screening programme for people living with HIV was associated with a significant reduction in the incidence of anal cancer, investigators from...

Ending HIV will require optimising treatment prevention tools – NIH experts

Optimal implementation of existing HIV prevention and treatment tools and continued development of new interventions are essential to ending the HIV pandemic, US National...

Weight gain while on ART: Demographic, HIV and treatment-related factors

People with HIV are living longer thanks to modern antiretroviral therapy (ART); however, studies have noted that initiating these treatment regimens can lead to...

A decade of HIV treatment has failed most high-risk young women

A review of HIV incidence among young people in east and southern Africa since antiretroviral treatment (ART) roll-out reveals failures to reach the highest-risk...

HIV treatment for over 60s – switching drugs could improve bone and kidney health

Switching from an antiretroviral treatment (ART) regimen containing tenofovir disoproxil fumarate (TDF) to a single-tablet regimen containing elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide (ECETA)...

Among those with private healthcare, ARV adherence declines over time

Overall, privately insured people with HIV have inadequate adherence to their daily antiretroviral (ARV) regimen during their first year on treatment and proceed to...

Exercise reduces symptoms of depression and anxiety in people with HIV

Exercise reduces symptoms of depression and anxiety in people living with HIV, according to the results of a meta-analysis. The research additionally showed that...

Many MSM in Africa are missing out on treatment

Despite improvements in HIV testing among men who have sex with men (MSM) in Africa, many are missing out on HIV treatment. This is...

Integrase inhibitors may increase the risk of diabetes

People who started antiretroviral therapy (ART) with a regimen that included an integrase inhibitor were more likely to develop diabetes mellitus, although this increased...

Young people receiving HIV treatment in SA increase 10-fold

Results of a study of more than 700,000 one to 19-year olds being treated for HIV infection suggests a ten-fold increase in the number...

Malawi: point-of-care testing results in more switches from failing treatment

Point-of-care viral load testing resulted in higher rates of switching and shorter periods on failing treatment than laboratory-based viral load testing in rural Malawi...

Benin: No sign of risk compensation in sex workers starting PrEP

Researchers found no evidence that female sex workers in Benin engaged in higher-risk behaviours after starting pre-exposure prophylaxis (PrEP). A novel methodology was used...

HIV/Aids: "Not the moment for complacency and triumphalism"

Now is not the time to get stuck in complacency and triumphalism over the gains made in the global HIV/Aids response, former president of...

SSA 'test and treat' programmes stumble

Programmes to scale-up HIV testing and treatment in countries in sub-Saharan Africa may have had less impact on new HIV infections than hoped, partly...

HIV increases risk of atrial fibrillation

HIV infection significantly increases the risk of atrial fibrillation (AF) – one of the most important causes of irregular heartbeats and a leading cause...

PrEP reduces HIV diagnosis rates in US cities by almost 16%

A study that compared pre-exposure prophylaxis (PrEP) usage rates in 19 US cities with the rates of HIV diagnosis has found that the cities...

Important to monitor kidney function in HIV patients doing well

The prevalence of impaired kidney function is low among white HIV-positive individuals with an undetectable viral load, Danish investigators report. However, the rate...

ART adherence — Is the gold standard still needed for viral suppression?

The levels of adherence to antiretroviral (ARV) regimens needed to achieve and maintain HIV viral suppression may be lower today than they previously were,...