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Introduction of PrEP reduces infections in women
The introduction of PrEP into a large study that was designed to find out if contraceptives increased the risk of HIV in women allowed...
PrEP success in Kenya and Uganda
A large cluster-randomised study which offered intensified healthcare, including PrEP, to 16 communities in Kenya and Uganda has reported a 74% reduction in HIV...
Islatravir keeps viral load suppressed
Islatravir, the first nucleoside reverse transcriptase translocation inhibitor, plus the non-nucleoside reverse transcriptase inhibitor doravirine (Pifeltro) kept viral load suppressed for 48 weeks with...
Rapid weight gain for people with HIV switching to tenofovir alafenamide
People who switched to tenofovir alafenamide (TAF) from the previous version of tenofovir (tenofovir disoproxil fumarate – TDF) experienced rapid weight gain regardless of...
Weight gain risk for people taking dolutegravir-based ARVs
People taking dolutegravir-based antiretroviral treatment have a substantially higher risk of becoming overweight or obese compared to other people with HIV and almost one...
Systemic TB treatment not superior to test guided treatment for HIV patients
In areas of sub-Saharan Africa and Asia, most HIV-infected patients present for care after already being severely immuno-compromised. After the initiation of antiretroviral therapy...
Infants newly diagnosed with HIV show high levels of resistance to ARVs
Pre-treatment drug resistance data for infants newly diagnosed with HIV from nationally representative surveys conducted between 2011 and 2016 in nine sub-Saharan African countries...
FDA paediatric version of dolutegravir to treat children
The US Food and Drug Administration (FDA) granted a new indication to a paediatric version of dolutegravir (Tivicay PD, ViiV Healthcare) tablets for oral...
US study finds PrEP regimen works
New data from Kaiser Permanente in San Francisco show that on-demand pre-exposure prophylaxis (PrEP) taken before and after sex – known as PrEP 2-1-1...
Recruitment to HIV trials 'not representative'
Recruitment to clinical trials that lead to the licensing of antiretroviral drugs is not representative of the global HIV pandemic, Aidsmap reports an international...
Long-acting ARV given as two monthly injectable PrEP protects against HIV
It’s not an Aids vaccine but it may be the closest thing to one so far. A long-acting antiretroviral drug given as an injection...
COVID-19 disruption of ARV treatments could double HIV deaths
A synthesis of five different studies that model the effect of a three- or six-month interruption of HIV services across sub-Saharan Africa finds that...
HIV-1 salvage therapy can omit NRTIs and remain efficacious and safe
People with HIV-1 infection (PWHIV) who have virologic failure can safely omit nucleoside reverse transcriptase inhibitors (NRTIs) in new regimens that include more than...
Review shows high prevalence of PTSD in people living with HIV
There is a high prevalence of post-traumatic stress disorder (PTSD) in people living with HIV, according to the first comprehensive systematic review and meta-analysis...
Paclitaxel plus ART shows superiority in treatment of advanced HIV-related Kaposi sarcoma
Intravenous paclitaxel plus antiretroviral therapy (ART) has clear advantages over alternative chemotherapy regimens for the treatment of advanced HIV-related Kaposi sarcoma in low- and...
Delaying treatment changes costs lives — SA study
Promptly switching antiretroviral therapy (ART) when individuals have viral rebound saves lives, Aidsmap reports an important study has found. Delayed switching more than doubled...
Integrase inhibitor-based ARV regimen reduces CVD risk in people with HIV
The risk of a serious cardiovascular event is reduced by a fifth in people taking an integrase inhibitor-based antiretroviral regimen compared to alternative drugs....
COVID-19 curtails HIV and immunotherapy efficacy trials
During the COVID-19 crisis, a number of the ongoing worldwide HIV vaccine and immunotherapy efficacy trials are being paused or curtailed, reports Aidsmap.
The HIV...
Spanish study finds little symptomatic or recovery difference in HIV COVID-19 patients
The first cases of COVID-19 identified in people living with HIV in Barcelona’s main hospital do not differ from the rest of the population...
Depressive disorders under-recognised and under-treated in people with HIV/Aids
People living with HIV/Aids are at increased risk of depressive disorders. But all too often, these conditions go unrecognised or untreated, suggests a literature...
PrEP protecting against HIV and hepatitis B – study
A retrospective cohort study of gay and bisexual men attending sexual health clinics in Japan shows that taking HIV pre-exposure prophylaxis (PrEP) not only...
Dolutegravir associated with hyperglycaemia in people switching first-line ART in Uganda
Hyperglycaemia was reported in Uganda among people switching first-line regimens to dolutegravir-based antiretroviral treatment (ART), in a letter to Lancet HIV, published online 24...
Adherence clubs help reduce viral load in post-partum SA women living with HIV
Adherence clubs were linked to a 30% reduction in high viral load among postpartum South African women living with HIV, Aidsmap reports the Conference...
Key risk factors for the emergence of renal dysfunction
Age over 50 years and pre-existing kidney function are the risk factors for the emergence of renal dysfunction while taking PrEP, according to data...
New approaches to dosing newborns with abacavir
8mg/kg of abacavir given twice daily to normal- and low-birth-weight new-borns with HIV in South Africa was safe and effective according to presentations in...
2 studies look at potential weight gain for women taking dolutegravir
Women with HIV gained significantly more weight in the year after giving birth if they were taking dolutegravir rather than efavirenz, Aidsmap reports two...
Trial shows safety and efficacy of ARV combinations in pregnancy
Dolutegravir-based antiretroviral treatment was associated with a higher rate of undetectable viral load at delivery in pregnant women, results of the IMPAACT 2010 trial...
Community-based treatment superior to clinic-based care in SA
Starting antiretroviral treatment on the day of diagnosis in a community setting and picking up medication from a mobile van resulted in superior rates...
TasP suppresses new HIV infections among gay and bisexual men in Australia
HIV treatment as prevention, as measured in community-level viral suppression, was strongly associated with a large drop in the number of new HIV infections...
Trial looks at community-based multi-month dispensing of ARVS
Dispensing antiretroviral drugs to people with suppressed viral load every six months is just as effective as dispensing medication every three months, a study...
Study results support clinical evaluation of GS-6207 as a long-acting ARV agent
A phase Ib study of Gilead Sciences' long-acting HIV-1 capsid inhibitor GS-6207 in people living with HIV demonstrated the drug’s potent antiviral activity, as...
African study on PrEP uptake and adherence
An interim survey of PrEP uptake and adherence in the SEARCH study in Kenya and Uganda, has found that just over a quarter of...
British HIV Association issues statement on COVID-19
Last week the British HIV Association (BHIVA), which represents medical professionals working in HIV in the UK, issued a statement about the new coronavirus...
'London Patient' steps out of the shadows
A year after the “London Patient” was introduced to the world as only the second person to be cured of HIV, The New York...
Group psychotherapy can dramatically improve depression in HIV+ people
Group support psychological therapy led by lay health workers is effective at alleviating symptoms of major depression among HIV-positive adults, according to research conducted...
Same day viral load testing linked to significant improvements in HIV treatment
A South African trial by researchers at the department of global health, University of Washington in Seattle finds 90% of people receiving rapid viral...
Partner reactions to HIV self-tests: NY and Puerto Rico study
Is using HIV self-tests with sexual partners an appropriate strategy that should be encouraged by health bodies? Could it help people who are already...
New Zealand needle exchange programmes keeps HIV rates low
Sustained, extremely low levels of HIV transmission among people who inject drugs, including gay and bisexual men, reflect the success of needle-exchange programmes and...
African hospitals report high death rate in HIV-associated meningitis
An evidence review has found that approximately half of hospital patients with cryptococcal, tuberculosis or pneumococcal meningitis died within two weeks or during hospitalisation....
Important to understand the pathogenesis of weight gain after ART
Dr Karam Mounzer, the chief medical officer of Philadelphia FIGHT, and the medical director of the Jonathan Lax Treatment Centre (the largest, community-based Philadelphia...