Top official admits low efficacy of China’s vaccines — then retracts

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China‘s top disease control official has said the efficacy of the country’s COVID vaccines is low, in a rare admission of weakness. BBC News reports that Gao Fu added that China was considering mixing vaccines as a way of boosting efficacy. Gao later said his comments had been misinterpreted.

China has developed four different vaccines approved for public use, though some trials abroad had suggested efficacy as low as 50% and more than 100m people in China have received at least one shot of the vaccine.

According to BBC News, Beijing has insisted the jabs are effective and said in March that obtaining visas would be easier for foreigners who have received a Chinese vaccine.

Gao Fu, head of the Chinese Centres for Disease Control and Prevention, is quoted in BBC News as saying the current vaccines “don’t have very high rates of protection”. Gao explained that steps to “optimise” the vaccine process could include changing the number of doses and the length of time. He also suggested combining different vaccines for the immunisation process.

But he later appeared to backtrack on his comments, saying that “protection rates of all vaccines in the world are sometimes high, and sometimes low”. He said his earlier admission that Chinese vaccines had a low protection rate were a “complete misunderstanding”.

BBC News reports that with little data released internationally, the effectiveness of the various Chinese vaccines has long been uncertain. Brazilian trials of the Sinovac vaccine CoronaVac for instance, showed an efficacy rate of around 50.4%, which is barely over the 50% threshold needed for regulatory approval by the World Health Organisation (WHO).

Interim results from late-stage trials in Turkey and Indonesia however, had suggested the efficacy rate of the Sinovac shot to be between 91% and 65%.

Western vaccines like the ones by BioNTech/Pfizer, Moderna have an efficacy rate of around 90% or higher while the UK‘s AstraZeneca jab is thought to be around 76%.

BBC News reports that so far, Sinovac’s CoronaVac jab has only been fully authorised for use by China. But Beijing is also offering its vaccines around the world and has already shipped millions of doses to a number of countries.

In Asia, the biggest takers are Indonesia, Malaysia, the Philippines, Thailand and Pakistan, while in the Americas, Brazil, Mexico, Chile, Colombia and Ecuador have also ordered millions of shot. In Europe, Turkey and Ukraine have signed large contracts for CoronaVac.

BBC News reports that the vaccine is thought to be particularly important for African countries where so far Zimbabwe, Somalia, Djibouti, Benin and Tunisia have received vaccines from China.

 

Full BBC News report (Open access)

 

See also MedicalBrief archives

China says early data shows Sinovac vaccine is safe in children

China offers 5m doses of Sinovac Biotech vaccine to SA

China defends Sinovac vaccine following poor results in Brazil

China’s drive for political influence through vaccines backfires

Despite safety fears, China inoculates with experimental vaccines

China tests its candidate COVID-19 vaccine on troops


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