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Oncology
3D mammograms detect more invasive breast cancers
After screening 15,000 women over a period of five years, a major clinical study in Sweden has shown that 3D mammography, or breast tomosynthesis,...
Newer oral contraceptives linked to reduced ovarian cancer risk
New types of combined oral contraceptives (containing both lower doses of oestrogens and newer progestogens) are associated with a reduced risk of ovarian cancer,...
Biomarker may predict response to ovarian cancer therapy
An international research team has identified an independent prognostic factor – cancer/testis antigen 45 (CT45) – as being associated with extended disease-free survival for women with...
Device shows promise as point-of-care detector of cancer
About half the size of a lunch box, the Tiny Isothermal Nucleic acid quantification sYstem (TINY) has shown promise as a point-of-care detector of...
Lower nutritional quality food associated with cancer risk
The consumption of foods with higher scores on the British Food Standards Agency nutrient profiling system (FSAm-NPS), reflecting a lower nutritional quality, is associated...
Breast cancer screening does not reduce mortality
Fewer and fewer women die from breast cancer in recent years but, surprisingly, the decline is just as large in the age groups that...
IARC report shows rising global toll of cancer
One in five men and one in six women around the world develop cancer during their lifetime. The Guardian reports that this is according...
Drinking from an early age linked to aggressive prostate cancer later in life
A study out of the University of North Carolina at Chapel Hill has found a link between early-life alcohol consumption and aggressive, high-grade prostate...
Blood test predicts how lymphoma respond to treatment
A blood test can predict which patients with a type of cancer called diffuse large B cell lymphoma are likely to respond positively to...
Experimental drug may help to prevent SOM
A new drug, called GC4419, although still in clinical trials, has already been designated by the US Food and Drug Administration as a "breakthrough...
Predictor indicates the potential success of melanoma treatment
In a study, researchers developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment...
Breast cancer deaths dropping but lung cancer deaths rising in women
An analysis of World Health Organisation data concludes that lung cancer deaths among women are set to rise by 43%.between 2015 and 2030, while...
Cancer patients using alternative therapies decrease survival chances
Cancer patients who use alternative therapies are be more likely to shun conventional treatments and risk their chances of survival, a study of 1,290...
Improving survival rates for patients with colorectal cancer
Patients with colorectal cancer tumours on the right side may have poorer five-year survival rates than those whose tumours are located on the left...
Blood test predicts specific prostate cancer treatment response
An international collaborative study between Lawson Health Research Institute, Memorial Sloan Kettering Cancer Centre, the Royal Marsden Hospital and Epic Sciences is one of...
Testosterone effective in combating cachexia in cancer patients
In patients with advanced cancer undergoing early standard of care therapy, adjunct testosterone improved lean body mass and was also associated with increased quality...
Antibody blood test to detect melanoma in its early stages
Australian researchers are claiming a breakthrough with a blood test for early stage melanoma. In a trial involving 105 patients with melanoma and 104 healthy...
Mammogram screening study supports the exclusion of low-risk women
A UK modelling study concluded that excluding the screening of low risk women would improve the quality of life gained, reduce over-diagnosis and save...
Ultrasound may be superior for treatment of prostate cancer
Using high energy ultrasound beams to destroy prostate cancer tumours may be as effective as surgery or radiotherapy, but with fewer side effects, a...
Fivefold improvement in glioblastoma survival with polio-virus therapy
A genetically modified poliovirus therapy developed at Duke Cancer Institute shows significantly improved long-term survival for patients with recurrent glioblastoma, with a three-year survival...
Environment predicts men's testosterone levels
Men's testosterone levels are largely determined by their environment during childhood found a UK study, challenging the theory that testosterone levels are controlled by...
Vitamin D linked to reduced breast cancer risk
Researchers at University of California – San Diego School of Medicine suggest higher levels of vitamin D are associated with decreasing risk of breast...
Higher body fat link to lower breast cancer risk in pre-menopausal women
While obesity has been shown to increase breast cancer risk in post-menopausal women, a large-scale study co-led by a University of North Carolina Lineberger...
Personalised glioblastoma vaccine may increase long-term survival
An international Phase III study led by researchers at the University of California – Los Angeles (UCLA) and at Northwest Biotherapeutics Inc has found...
Study on first birth cohort to receive HPV vaccine
Girls in the first birth cohort to receive the HPV vaccine showed a lower degree of dysplasia which may eventually lead to cervical cancer...
Immune checkpoint inhibitor shrinks incurable skin cancer tumours
Clinical trials show that an immune checkpoint inhibitor shrinks the tumours of nearly half of patients with incurable, advanced cutaneous squamous-cell carcinoma, an international...
Little benefit from frequent monitoring of post-Tx prostate cancer
Prostate cancer patients who were monitored more frequently after treatment did not live significantly longer than patients who were monitored once a year, according...
No benefit from chemo for 70% of those with early breast cancer — TAILORx
Findings from the ground-breaking Trial Assigning Individualised Options for Treatment (Rx) (TAILORx) trial, show no benefit from chemotherapy for 70% of women with the...
Aspirin with acid reducers helps acid reflux patients slow cancer advance
Taking aspirin with acid reducers can help patients with chronic acid reflux slow the advance of cancer of the oesophagus, the tube from the...
Novel breast cancer Tx approach led to complete regression in patient
A novel approach to immunotherapy developed by researchers at the National Cancer Institute (NCI) has led to the complete regression of breast cancer in...
Gene test could help early breast cancer patients forgo chemo
A 21-gene test performed on tumours could enable most patients with the most common type of early breast cancer to safely forgo chemotherapy, according...
Immunotherapy may halt spread of prostate cancer — UK trial
More than a third of men with an advanced form of prostate cancer were still alive and one-in-10 had not had further growth after...
Antibiotics may affect some cancer treatment outcomes
Cancer patients who took antibiotics during immunotherapy treatment lived about half as long as those who avoided the drugs, The Guardian reports a new...
Ground-breaking immunotherapy clears advanced breast cancer
A woman with advanced breast cancer which had spread around her body has been completely cleared of the disease by a ground-breaking therapy that...
Blood test may detect 10 types of cancer before tumour develops
A blood test able to detect 10 types of cancer years before a person falls ill could become available on the UK's National Health...
Non-aspirin NSAID use linked to shorter survival rates in mRCC
A University of California study has indicated that non-aspirin NSAID use was associated with shorter overall survival in patients with metastatic renal cell carcinoma...
Arterial thrombosis associated with increased incidence of cancer
Lower limb arterial thrombosis was a marker of occult cancer, especially lung cancer, and was an adverse prognostic factor for mortality in common cancers,...
Immunotherapy and chemo drug combo increases lung cancer survival rates
The immunotherapy drug pembrolizumab, when combined with chemotherapy, doubles survival in patients with non-squamous non-small cell lung cancer (NSNSCLC) lacking genetic changes in the...
Investigational drug safely and effectively treats RET-driven cancers
A phase I, first-in-human study led by The University of Texas MD Anderson Cancer Centre reveals for the first time, an investigational drug that...
Chip-based blood test for multiple myeloma may relegate bone biopsy
The diagnosis and treatment of multiple myeloma, a cancer affecting plasma cells, traditionally forces patients to suffer through a painful bone biopsy. During that...