Thursday, 22 February, 2024
HomeEndocrinologyExperiment shows new way forward in treating diabetes

Experiment shows new way forward in treating diabetes

Scientists have converted human gut cells into insulin producers by turning off one gene in an experiment that suggests a new way forward in treating diabetes. [s]Business Day[/s] reports that using a miniature model of the human intestine, only a few millimetres in size and made from stem cells, the scientists at [b]Columbia University’s Naomi Berrie Diabetes Research Centre[/b] deactivated a gene in the cells tied to metabolic regulation called FOXO1. Once disabled, the cells began producing insulin. The method raises the possibility of replacing insulin-making pancreatic beta cells lost in diabetics by using a drug to retrain patients’ existing cells..

[link url=http://www.bdlive.co.za/life/health/2014/07/01/fighting-diabetes-may-be-a-matter-of-guts]Full Business Day report[/link]
[link url=http://www.nature.com/ncomms/2014/140630/ncomms5242/full/ncomms5242.html]Nature Communications abstract[/link]

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