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Vaccination may ease Long COVID patients — Small Bristol study

For those suffering from the effects of long COVID, this has been one of the worst years of their lives. But reports The Daily...

Inflammatory bowel disease biologic blunts immune response to COVID-19 — NHS study

Infliximab, a powerful biologic that is used to treat inflammatory bowel disease (IBD), blunts the body's immune response to COVID-19 infection, indicates research. This...

COVID-19 antibodies discovered in stray cat and dog — Small Brazil study

Study details Neutralizing antibodies for SARS-CoV-2 in stray animals from Rio de Janeiro, Brazil Helver Gonçalves Dias, Maria Eduarda Barreto Resck, Gabriela Cardoso Caldas, Alessandro Fioretti...

AstraZeneca claims 79% prevention efficacy in US vaccine trial

The AstraZeneca US Phase III trial of AZD1222 demonstrated statistically significant vaccine efficacy of 79% at preventing symptomatic COVID-19 and 100% efficacy at preventing...

Regeneron antibody cocktail cuts COVID-19 hospitalisation and deaths

New late-stage trial data show Regeneron and Roche’s antibody cocktail against COVID-19 cut hospitalisation or death by 70% versus a placebo in non-hospitalised patients,...

Schools guidance to reflect new evidence on distancing in classrooms — CDC

The US Centres for Disease Control and Prevention (CDC) is updating K–12 school guidance to reflect the latest science on physical distance between students...

High vitamin D levels may protect against COVID-19, especially for Black people

A study at the University of Chicago Medicine has found that when it comes to COVID-19, having vitamin D levels above those traditionally considered...

South Africa variant elicits cross-reactive neutralising antibodies

Penny Moore was one of the first scientists to show that a coronavirus variant identified in South Africa could dodge the immune system. So,...

Progesterone therapy may improve COVID-19 outcomes for men — Pilot study

COVID-19 disproportionately affects men compared with women, raising the possibility that a hormone like progesterone may improve clinical outcomes for certain hospitalised men with...

Efficacy of Oxford AstraZeneca COVID-19 vaccine — Wits University trial

Findings of a study in the Oxford AstraZeneca COVID-19 vaccine trial have been published. This is a landmark study in so far as being...

Increased mortality in UK variant of SARS-CoV-2 – Large database analysis

The B.1.1.7 variant of SARS-CoV-2, which was first identified in the UK, may be associated with an increased risk of death, a study suggests....

COVID-19 numbers may double if asymptomatic adults added — US insurer analysis

A study evaluating asymptomatic adults for COVID-19 would add another 16m to the total number of SARS-CoV-2 infections in the US, at least up...

Efficacy and safety of ruxolitinib in COVID-19 associated ARDS — DEVENT study

Incyte has announced results from the Phase 3 DEVENT study evaluating the efficacy and safety of ruxolitinib (5mg and 15mg) plus standard of care...

COVID-19's link with audio-vestibular problems, including tinnitus — Systematic review

Hearing loss and other auditory problems are strongly associated with COVID-19 according to a systematic review of research evidence led by The University of...

ECDC report: Face mask effectiveness in reducing COVID-19 transmission

Key messages: The role of face masks in the control and prevention of COVID-19 remains an issue of debate. Prior to COVID-19, most studies assessing...

Aspirin use for CVD may reduce risk of COVID-19 infection – Israeli study

Aspirin is an established, safe, and low-cost medication in long-standing common use in prevention and treatment of cardiovascular diseases, and in the past a...

Novavax trials in SA and UK confirm high efficacy against original and variants

Results of the Novavax COVID-19 vaccine trial in South Africa and UK have confirmed high levels of efficacy against the original and variant COVID-19....

Pfizer vaccine neutralises Brazil variant but less robust against SA variant

Pfizer's coronavirus vaccine does successfully neutralise the more contagious P.1 variant of the virus recently discovered in Brazil, MedicalXpress reports new research shows. Pfizer...

UK variant associated with a significantly higher mortality — Two studies

The highly infectious variant of COVID-19 discovered in Kent, which swept across the UK last year before spreading worldwide, is between 30% and 100%...

High COVID-related depression, anxiety and PTSD among health workers — Meta-analysis

A new systematic review of 65 studies from around the world involves a total of 97,333 health care workers and finds that 1 in...

More evidence of lack of Vitamin D efficacy for COVID-19 — Two studies

The idea that vitamin D supplements can reduce susceptibility to, and the severity of, COVID-19 is seductive – it offers a simple, elegant solution...

Blood biomarkers offer early indicator of severe COVID-19 — Yale

When patients with COVID-19 arrive in emergency rooms, there are relatively few ways for doctors to predict which ones are more likely to become...

Prioritising oldest for COVID-19 vaccines saves more lives, potential years of life

Challenging the idea that older people with shorter life expectancies should rank lower in coronavirus immunisation efforts, University of California-Berkeley research shows that giving...

Statin use associated with 50% increased survival in severe COVID-19

People who took statins to lower cholesterol were approximately 50% less likely to die if hospitalised for COVID-19, a study by physicians at Columbia...

Promising early findings from Merck/Ridgeback Phase 2a trial of oral COVID-19 therapeutic

Merck, known as MSD outside the US and Canada, and Ridgeback Biotherapeutics LP have announced preliminary results from Ridgeback’s Phase 2a randomised, double-blind, placebo-controlled...

Baricitinib plus remdesivir in reducing recovery time in COVID-19 patients — ACTT-2 trial

Baricitinib plus remdesivir was superior to remdesivir alone in reducing recovery time and accelerating improvement in clinical status among patients with COVID-19, notably among...

WHO expert panel strongly advises against use of hydroxychloroquine to prevent COVID-19

The anti-inflammatory drug hydroxychloroquine should not be used to prevent infection in people who do not have covid-19, says a World Health Organisation (WHO)...

Azithromycin doesn't reduce recovery time or hospitalisation risk — PRINCIPLE trial

Treatment with azithromycin had little effect on reducing the time to recovery or risk of hospitalisation in patients with suspected COVID-19, according to a...

22% of children with COVID or MIS-C had neurologic conditions — US hospital study

Among US children and teens hospitalised with COVID-19 or its related multisystem inflammatory syndrome in children (MIS-C), 22% had neurologic conditions, most of them...

Ocular swabs detect SARS-CoV-2 RNA in 57% of COVID-19 cases — Italian study

Genetic evidence of SARS-CoV-2, the virus that causes COVID-19, was found on the ocular surface of 57% of Italian COVID-19 patients, according to a...

Iranian trial of efficacy and safety of Ivermectin in patients with mild and moderate COVID-19

Researchers at the Hormozgan University of Medical Sciences, Bandar Abbas, Iran are trialling the efficacy and safety of Ivermectin in patients with mild and...

Smell tests should be part of routine COVID-19 screenings — STAT News

Temperature checks could well join the long list of fumbled responses to the pandemic, from the testing debacle to federal officials’ about-face on masks,...

Clinical and demographic risk factors for COVID-19 deaths in 17 million NHS patients

Risk factors associated with COVID-19 death, based on analyses of full pseudonymized health records of 17m adults in England, are reported in a study...

COVID-19 herd immunity may be unachievable — Spanish study of 61,000 people

Spain's large-scale study on the coronavirus indicates just 5% of its population has developed antibodies, strengthening evidence that a so-called herd immunity to COVID-19...

NICD report: Epidemiology and clinical characteristics of COVID-19 in SA children

According to a National Institute of Communicable Diseases (NICD) report, children made up less than 7% of all reported COVID-19 cases in South Africa and...

Groote Schuur doctors on benefits of high-flow nasal oxygen — Spotlight report

Spotlight reports that doctors at two of the Western Cape’s most impacted COVID-19 hospitals say they have seen positive outcomes from using high-flow nasal...

Problematic response of the elderly to COVID-19 — 27-country survey

Survey results from 27 countries suggest that, despite their increased risk of severe illness due to COVID-19, elderly people are not more willing to...

WHO discontinues hydroxychloroquine and lopinavir/ritonavir treatment arms for COVID-19

The World Health Organisation (WHO) has announced that it has accepted the recommendation from the Solidarity Trial’s International Steering Committee to discontinue the trial’s...

JAMA study: 35% of excess US deaths tied to causes other than COVID-19

Since COVID-19’s spread to the US earlier this year, death rates in the US have risen significantly. But deaths attributed to COVID-19 only account...

Immunity to COVID-19 may be higher than tests have shown — Karolinska Institutet

Research from Karolinska Institutet and Karolinska University Hospital shows that many people with mild or asymptomatic COVID-19 demonstrate so-called T-cell-mediated immunity to the new...