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Oncology
Amazon involved in new cancer vaccine clinical trial
Amazon is working with the Fred Hutchinson Cancer Research Centre to develop cancer vaccines in a new clinical trial aimed at finding “personalised vaccines”...
US study finds ‘microbial link’ between Western diet and colon cancer
A recent study suggests that intestinal microbiota may be at the heart of the association between a Western diet and colon cancer.
A healthy diet...
Contaminants in fish, like tuna, linked to higher skin cancer risk – US study
Heavier consumption of fish, including tuna and other non-fried fish, has been associated with a higher risk of melanoma, findings from a large prospective...
US cancer trial’s unexpected result: remission in every patient
It was a small trial, just 18 rectal cancer patients, all of whom took the same drug. But the results were astonishing. The cancer...
mRNA vaccine can recognise neoantigens in pancreatic cancers – US study
BioNTech has announced initial data from an ongoing study which shows that mRNA-based individualised neoantigen specific immunotherapy (iNeST) vaccines can be used to stimulate...
'Practice-changing' results for breast cancer with Enhertu treatment
The drug Enhertu has been shown to enable women with advanced breast cancer to live six months longer than others treated with conventional chemotherapy, new...
'Engineered' drug trains immune system to attack tumours but spare healthy cells
Researchers have designed a method to keep one promising cancer drug from wreaking havoc by “masking” it until it reaches a tumour, thereby preventing...
Patient’s opinion on cancer treatment often under-valued – Australian study
A breast cancer patient’s perspective on their physical well-being can provide a better indication of their response to cancer treatment than clinician-based tools, a...
Serious blood clot risk for men with prostate cancer – Swedish cohort study
Men with prostate cancer have a 50% higher risk of developing serious and potentially fatal blood clots during the five years after their cancer...
Men’s breast cancer may be linked to infertility – ICR study
The risk of invasive breast cancer in men may be associated with self-reported infertility in the male partner, found research from The Institute of...
Bacterial link to possible rapid progression of prostate cancer – East Anglia study
Researchers led by the University of East Anglia performed genetic analyses on the urine and prostate tissue of more than 600 men with and...
Promising ‘killer’ cancer treatment targets hard-to-treat tumours – UK trial
Researchers at the Institute of Cancer Research (ICR), London, and the Royal Marsden NHS Foundation Trust who have been trialling the new drug, known...
Nitrites and nitrates linked to higher cancer risk – French study
A French study, which investigated the relationship between intake of nitrites and nitrates (all sources combined) and the risk of cancer, found that food...
Blood test that screens for DNA fragments of tumour billed as ‘new frontier’ in cancer screening
A blood test is being billed as a new frontier in cancer screening for healthy people – it looks for cancer by checking for...
False positive readings for 50% of 3D mammograms over a decade of screening
Half of all women getting 3D mammograms will experience a false positive over a decade of annual screening, according to a study published in...
Height should be considered a risk factor for colorectal screening – Meta-analysis
A meta-analysis by Johns Hopkins Medicine researchers adds to evidence that taller adults may be more likely than shorter ones to develop colorectal cancer...
Ultrasound scan versus MRI scans for prostate cancer – UK paired-cohort study
An ultrasound scan was able to diagnose most prostate cancer cases with good accuracy in a clinical trial involving 370 men, reports a study...
Enhertu improved progression-free and overall survival in metastatic breast cancer
The first HER2-low metastatic breast cancer Phase III results for AstraZeneca and Daiichi Sankyo’s Enhertu offer potential to redefine how the disease is classified...
Darolutamide improves survival in metastatic prostate cancer
Results from an international, randomised, double-blind, placebo-controlled, phase 3 clinical trial provide hope for men suffering from usually fatal metastatic hormone-sensitive prostate cancer. The...
Keytruda boosts event-free survival by up to 39% in early triple-negative breast cancer
In patients with early triple-negative breast cancer, pembrolizumab (Keytruda) with chemotherapy cuts recurrence by up to 39%, found a three-year follow-up of the Keynote-522 trial,...
Decade-long leukaemia remissions with CAR T-cell therapy – Landmark study
Two of the first human patients treated with a therapy that engineers immune cells to target specific types of cancer still possess cancer-killing cells...
Novel combination treatment improves survival in pancreatic cancer – Animal study
Mice with pancreatic tumours given a novel combination treatment lived 25% longer than those given just high intensity, focused ultrasound (HIFU), and 35% longer...
Oral anticoagulants decrease cancer-associated thrombosis – Mayo Clinic meta-analysis
Direct oral anticoagulants significantly decreased cancer-associated venous thrombosis recurrence without significantly increasing bleeding, found an ongoing Mayo Clinic study.
Thrombotic outcomes increase mortality in cancer...
Immunotherapy before liver cancer surgery kills tumours – Mount Sinai clinical trial
Immunotherapy given before surgery caused liver cancer tumours to die off in one-third of the patients enrolled in a first-of-its-kind clinical trial, Mount Sinai...
High coffee consumption associated with lower endometrial cancer risk – Meta-analysis
Higher coffee consumption is linked with a lower risk of endometrial cancer, a type of cancer that begins in the lining of uterus, according...
Inhaled CBD shrinks glioblastoma in animal model
Inhaled CBD (cannabidiol) shrinks the size of the highly aggressive, lethal brain tumour glioblastoma in an animal model by reducing the essential support of...
Severe outcomes in vaccinated cancer patients with breakthrough COVID
The first study to evaluate the clinical characteristics and outcomes of fully vaccinated patients with cancer who had breakthrough COVID-19 infections indicates they remained...
Glioblastoma: First trial for oral cannabinoids plus chemotherapy
Hundreds of cancer patients at 15 UK hospitals will be given Sativex, an oral spray containing cannabinoids, along with chemotherapy to treat their aggressive...
HPV vaccine cuts cervical cancer by nearly 90% — UK population registry study
The human papillomavirus (HPV) vaccine is cutting cervical cancer incidence by nearly 90%, the first real-world data from the UK, published in The Lancet,...
Inexpensive drug significantly enhanced radiation therapy effectiveness in brain metastases — Small trial
Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in...
Under-35s have greater risk of breast cancer spreading — Meta-analysis
Women under 35 diagnosed with breast cancer face a higher risk of it spreading, according to the first global study of its kind, presented...
Low glycaemic diet inhibits tumour growth in animal study
Calorie restriction, but not a ketogenic diet, inhibits the growth of tumours in a mouse model of pancreatic cancer, found a study in Nature.
Although...
Exercise may alleviate ‘chemo brain’ in breast cancer — Washington University study
Regular exercise may help lessen “chemo brain” among women being treated for breast cancer, according to a large-scale study of the associations between physical...
Adavosertib may delay tumour regrowth in inoperable metastatic colorectal cancer
Adavosertib, taken as a daily pill, may delay tumour regrowth among patients with an aggressive sub-type of inoperable metastatic colorectal cancer, found a UK...
ESMO 2021: Highly promising results against breast and ovarian cancer
AstraZeneca’s Enhertu demonstrated a 72% reduction in the risk of disease progression or death in HER2-positive metastatic breast cancer according to trial results presented...
Increased colon cancer risk extends to second- and third-degree relatives
Having second- or third-degree relatives with colorectal cancer significantly increases the risk of developing the disease, found a study in Cancer Epidemiology. Early screening...
Antibiotic use linked to increased risk of colon cancer — Swedish Colorectal Cancer Registry
There is a clear link between taking antibiotics for more than six months and an increased risk of developing colon cancer within the next...
Antibiotic use linked to increased risk of colon cancer — large Swedish analysis
There is a clear link between taking antibiotics and an increased risk of developing colon cancer within the next five to 19 years, found...
Statins may significantly improve survival in triple-negative breast cancer
A significant association was found between cholesterol-lowering drugs, commonly known as statins, and survival rates of triple-negative breast cancer patients, found a study led...
High Intensity Training regimen may inhibit prostate cancer growth — ERASE trial
Rigorous exercise not only boosted cardiorespiratory fitness, but also improved indicators of prostate cancer biochemical progression in patients undergoing active surveillance, according to results...