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Injections 2.5x safer when nurses use revamped guidelines

When UK nurses followed modified guidelines that present the same information in a more user-friendly way, nearly two and half times more doses were given without mistakes.

The UK's National Health Service (NHS) is changing the way it writes its guidelines for giving injections in hospitals. A University of Bath study, funded by the National Institute for Health Research (NIHR), found that hospital nurses make far fewer mistakes when administering medicines intravenously if they follow instructions written with nurses in mind. Researchers used a process called 'user testing', which identifies where mistakes are being made and introduces changes so the instructions are easier to use.

Current NHS guidelines on intravenous injections are written by pharmacists with little input from their primary audience – nurses. These instructions can be confusing or overly complicated, which contributes to 30-50% of intravenous doses being incorrect in some way.

Injection-related mistakes form a major part of the 237m medication errors that occur annually in England, and they can arise because nurses struggle to find relevant, unambiguous information in the NHS guidelines, explained Dr Matthew Jones, who led the research from the University's department of pharmacy and pharmacology in collaboration with colleagues from the Universities of Leeds and Strathclyde, and University College London School of Pharmacy.

"When nurses follow modified guidelines that present the same information in a more user-friendly way, nearly two and half times more doses are given without mistakes," he said. "As a bonus, the injection procedure is also completed faster and nurses feel more confident about their decisions."

He added: "Current instructions are usually written by pharmacists using a format and language that makes immediate sense to other pharmacists, but not necessarily to nurses.

"Different professions think about things in different ways as a result of the different training they receive, and we need injection guidelines to be written in a way that is understood by nurses because they prepare and administer most injections."

In developing the Bath study, researchers collaborated with Luto Research, a University of Leeds spin-out company with expertise in user testing. The study involved 273 nurses and midwives who regularly administer injections from four NHS hospitals.

Participants were taken part way through a shift and asked to give an injection to a rubber dummy simulating a patient's arm. Around half of participants were given the current NHS guidelines and the other half the modified guidelines. A researcher watched to identify guideline-related errors.

"The results make it clear that busy, stressed staff need information to be presented in a way that is easy to understand and quick to find," said Jones. "User testing allowed us to identify where the information needed improving and how we could do that."

The study's findings have triggered a review of how injection guidelines are produced for the NHS Injectable Medicines Guide. This website-based guide provides information on the correct procedures for preparing and administering over 350 intravenous medicines in over 120 hospitals. It is accessed approximately 3-million times per year, mostly by hospital nurses.

Jones said: "To improve patient safety, most injectable medicines' guidelines should be user-tested. This is particularly important when high-risk and complex decisions are being made."

According to the World Health Organisation, unsafe medication practices and medication errors are a leading cause of injury and avoidable harm in health care systems across the world. Globally, the cost associated with medication errors is estimated at US$42 billion every year.

Abstract
Background: User-testing and subsequent modification of clinical guidelines increases health professionals’ information retrieval and comprehension. No study has investigated whether this results in safer care.
Objective: To compare the frequency of medication errors when administering an intravenous medicine using the current National Health Service Injectable Medicines Guide (IMG) versus an IMG version revised with user-testing.
Method: Single-blind, randomised parallel group in situ simulation. Participants were on-duty nurses/midwives who regularly prepared intravenous medicines. Using a training manikin in their clinical area, participants administered a voriconazole infusion, a high-risk medicine requiring several steps to prepare. They were randomised to use current IMG guidelines or IMG guidelines revised with user-testing. Direct observation was used to time the simulation and identify errors. Participant confidence was measured using a validated instrument. The primary outcome was the percentage of simulations with at least one moderate-severe IMG-related error, with error severity classified by an expert panel.
Results: In total, 133 participants were randomised to current guidelines and 140 to user-tested guidelines. Fewer moderate-severe IMG-related errors occurred with the user-tested guidelines (n=68, 49%) compared with current guidelines (n=79, 59%), but this difference was not statistically significant (risk ratio: 0.82; 95% CI 0.66 to 1.02). Significantly more simulations were completed without any IMG-related errors with the user-tested guidelines (n=67, 48%) compared with current guidelines (n=26, 20%) (risk ratio: 2.46; 95% CI 1.68 to 3.60). Median simulation completion time was 1.6 min (95% CI 0.2 to 3.0) less with the user-tested guidelines. Participants who used user-tested guidelines reported greater confidence.
Conclusion: User-testing injectable medicines guidelines reduces the number of errors and the time taken to prepare and administer intravenous medicines, while increasing staff confidence.

Authors
Matthew D Jones, Anita McGrogan, DK Raynor, Margaret C Watson, Bryony Dean Franklin

 

[link url="https://www.bath.ac.uk/announcements/injections-are-two-and-a-half-times-safer-when-nurses-use-revamped-guidelines/"]University of Bath material[/link]

 

[link url="https://qualitysafety.bmj.com/content/early/2020/06/30/bmjqs-2020-010884"]BMJ Quality & Safety abstract[/link]

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