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Reduction of new HIV infections in SSA's youth is far off-track
Africa is far off-track in reducing new HIV infections among children and young people and is unlikely to reduce new infections in young people...
Clues to ways prevention programmes could be optimised
Substantial decreases in HIV diagnoses in key cities show the way to elimination of new HIV diagnoses in gay men, a workshop at the...
Pricing agreement lowers cost of diagnostic testing in emerging economies
A breakthrough pricing agreement will significantly reduce the cost of diagnostic testing for HIV/Aids, hepatitis and cervical cancer for millions of people in low-...
Kaposi's sarcoma remains a concern for people with HIV
A small proportion of people living with HIV continue to develop Kaposi's sarcoma (KS), a cancer linked to immune suppression, according to studies presented...
Encouraging results from Merck's doravirine trial
Doravirine, the experimental antiretroviral developed by Merck, suppressed HIV at a higher rate compared with Norvir (ritonavir)-boosted Prezista (darunavir) 96 weeks into a clinical...
'Dangerous complacency' risks resurgence of HIV pandemic — Lancet Commission
A ‘dangerous complacency’ in response to the global HIV pandemic is risking a resurgence of the disease, found theLancet Commission, led by the International...
The 'favoured child' still desperately needs intervention
Almost four decades on and despite having benefited as favoured child of global health funding, the HIV/Aids epidemic is far from over, writes Professor Linda-Gail...
Persistently high rate of HIV infections scares SA's health minister
The high rate of HIV infections in South Africa has left Health Minister Dr Aaron Motsoaledi “scared”. City Press reports that Motsoaledi was addressing...
Donor cuts could threaten global progress on HIV
If donor government funding for HIV continues to fall, nearly two decades of progress against the disease will be in jeopardy, according to new...
HIV data from sub-Saharan Africa gives reasons for hope
Researchers and public health experts presented promising new data on the HIV epidemic and response in sub-Saharan Africa at the 22nd International AIDS Conference...
Insufficient evidence for recommendations on breastfeeding for mothers with HIV
Research is urgently needed to provide clear recommendations on breastfeeding to mothers with HIV who have an undetectable viral load on antiretroviral treatment, a...
HIV-positive children more likely to have developmental disabilities
HIV-positive children in South Africa are more likely to have developmental disabilities compared to children who are HIV negative, according to researchers at Columbia...
MSM show preference for using HIV self-testing kits
A study that gave HIV self-testing kits out to 127 mainly young men who have sex with men (MSM) in two regions in north-east...
Reduced dose darunavir safe and effective in viral suppression
In well-suppressed, treatment-experienced adults with HIV, decreasing the dose of ritonavir-boosted darunavir (darunavir/r) from the standard dose is associated with a high rate of...
Dolutegravir in people who experienced virological failure with older integrase inhibitors
Antiretroviral regimens containing dolutegravir, a next-generation integrase inhibitor, are durable and achieve high rates of viral suppression in people who experienced virological failure with...
Novel online prevention programme cut STIs by 40%
A novel online HIV prevention programme with spicy soap operas and interactive games – like a rising thermometer of sexual risk – reduced sexually...
Most physicians willing to prescribe PrEP to teens
US regulators said in May that a pill that helps prevent infection with HIV is safe for use by adolescents, and a study suggests...
Important to inform children of their seropositive status
School-age children should be informed of their seropositive status and disclosure for younger children should occur incrementally, according to a research review.
In 2016, approximately...
Rilpivirine better tolerated, less toxic than efavirenz in first-line ART
Rilpivirine is better tolerated, less toxic and more durable than efavirenz when used as part of a first-line antiretroviral regimen, investigators from the Infectious...
HIV factors not associated with increased risk of suicide in France
Approximately 4% of deaths among people with HIV in France are due to suicide, investigators report. Suicide incidence remained stable over 13 years of...
New alert on using darunavir/cobicistat during pregnancy
Janssen Pharmaceuticals has issued a new alert against using darunavir/cobicistat during pregnancy. This new contraindication is based on significantly reduced plasma levels of...
Long periods of viral suppression reduces cancer risk in HIV population
Early, sustained antiretroviral therapy (ART), which results in long-term viral suppression, helps to prevent Aids-defining cancers and also non-Aids-defining cancers, to a lesser degree....
Two-drug HIV regimen effective in treatment-naive patients
ViiV Healthcare has released data from two phase 3 trials that showed a once-daily, two-drug regimen of dolutegravir and lamivudine was non-inferior to a...
Syringe programmes an important tool in preventing HIV outbreaks
A study by researchers investigating the 2015 HIV outbreak in Scott County, Indiana, found that a syringe services programme is an important tool to...
Predictive computer models to optimise HIV therapy
New predictive computer models designed to optimise HIV therapy in countries with limited healthcare resources have been published online. The models, which were developed...
Understanding how partnerships help with ART adherence
As more countries recommend the use of treatment partners to help people living with HIV adhere to their antiretroviral treatment, there is a need...
Pro-140 on track to be part of combination MDR/HIV treatment
Positive results support the continued development of PRO 140 – CytoDyn’s investigational humanised monoclonal antibody for the treatment of patients with HIV who are...
Hepatitis B or raised liver enzymes predict liver toxicity when TB drug is combined with ART
The risk of liver toxicity in people with HIV taking antiretroviral therapy and isoniazid preventive therapy for tuberculosis is strongly associated with either hepatitis...
Potential interactions between ART and other medications
Over half of older HIV-positive people are at risk of experiencing an interaction between their anti-HIV drugs and medications taken for the treatment of...
WHO, EMA and FDA warn on 'wonder' drug and birth defects
Within a week, the 'revolutionary' HIV drug dolutegravir has gone from being highly regarded to being the subject of international warnings. Health-e News reports that recent...
Switzerland's successful HIV prevention policy for IV drug users
Switzerland's pragmatic HIV prevention policy for intravenous drug users has been extremely successful. Medical Xpress reports that thousands of HIV infections and Aids cases...
Women with limited power over decisions could benefit from PrEP
A study among pregnant women in South Africa has found many lack control over condom use – and would be willing to use pre-exposure...
PrEP may make it hard to detect HIV infection
It may be very difficult to tell if someone who has just started HIV pre-exposure prophylaxis (PrEP) has actually caught HIV just before or...
The risk of hypertension in people with HIV
People with HIV are more likely than people without the virus to have high blood pressure, in part because of treatments and repercussions of...
Warning of birth defect risk to women receiving dolutegravir in early pregnancy
The US Food and Drug Administration (FDA) has issued a safety alert warning patients and providers about a potential risk for neural tube birth...
Possible to provide good quality public sector care to the MSM group
Research has shown that addressing HIV in certain key populations is a priority in order to end the epidemic in the general population. Kate...
PHIA data provide a robust picture of country-level HIV epidemics
In a perspective recently published in the New England Journal of Medicine, ICAP researchers Drs Jessica Justman, Owen Mugurungi, and Wafaa El-Sadr at the...
No or low risk of HIV transmission from spitting and biting
There is no risk of transmitting HIV through spitting, and the risk from biting is negligible, according to research. An international team of investigators...
Studies question the benefits of TAF over TDF
The claimed health benefits of tenofovir alafenamide (TAF) over tenofovir disoproxil fumarate (TDF) could be something of a mirage, writes Benjamin Ryan, editor at...
Treating major depressive disorder improves outcomes in HIV patients
Despite the prevalence of depression in people with HIV (estimates of up to 42%), few data exist on antidepressant efficacy in this population.1 Previous...