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New contract sees big drop in price for HIV medicines

The national Department of Health (DOH) has managed to secure a significant reduction in prices for antiretroviral medicines that treat HIV, with the price of the regimen that is prescribed to most new patients (tenofovir/lamivudine/dolutegravir – TLD) dropping over 30%, from R99 to R68.

By comparison the regimen costs well over R250 in the private sector, GroundUp reports.

TLD is recommended by the World Health Organisation as the preferred first-line regimen for adults living with HIV.

Over 4m South Africans are using this regimen, according to statistics from the DOH. There are about over 5.5m people receiving treatment for HIV, and 8m people living with the virus in the country.

Prices of ABC/3TC, commonly used to treat children with HIV, also fell with the DOH’s new contract.

Khadija Jamaloodien, director of the Affordable Medicines Directorate in the DOH said South Africa is the biggest buyer of ARVs in the world. She said because of the sheer number of people needing ARVs, the department was able to bring the price down.

“Our volumes are just so huge that it makes it more efficient for manufacturers to be able to supply at reasonable prices,” said Jamaloodien.

She said another reason the department was able to reduce the price was that the manufacturers were applying for a three-year contract with “a certainty of demand”. She said constant communication with manufacturers about changes in demand also helped. If demand is likely to be reduced, the department would inform manufacturers who then would not “sit with stock that they are going to have to write off”.

The contract, which is already being executed, was awarded from July 2022 and ends in June 2025.

The department is purchasing all ARVs for much lower prices than on the previous contract. In the late 1990s it cost several thousand rand per month for a standard ARV regimen, one much inferior to TLD. The drugs were only available then in the private sector.

Jamaloodien said lower prices meant that the department could serve more patients and provide more medicines within the same budget envelope. (ARVs are provided free to public sector patients.)

Juliet Houghton, CEO of the Southern African HIV Clinicians Society (SAHCS), praised the DOH’s efforts to secure the ARVs so cheaply. She said a “healthy” degree of competition between manufacturers also helped drive prices down.

Houghton added that the reduction in prices “offers an opportunity to reinvest some of the savings into more expensive, particularly prevention drugs, that are coming”.

Jamaloodien said that the injectable pre-exposure prophylaxis (PrEP) medicines are not yet registered with South African Health Products Regulatory Authority (SAHPRA).

 

GroundUp – HIV medicine prices have reduced dramatically – Open Access

 

See more from MedicalBrief archives:

 

Cost and uncertainty over uptake bedevil Africa’s uptake of injectable PrEp

 

Trial looks at community-based multi-month dispensing of ARVS

 

Landmark UNAIDS pricing deal to accelerate HIV treatment

 

 

 

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