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Cardiovascular
Salt substitute reduces stroke, CV events and mortality risk — SSaSS trial
Among those with previous stroke or older than 60 and with high blood pressure, the rates of stroke, major cardiovascular (CV) events, and death...
Association between womenʼs middle-age height loss and greater risk of death
Women who experience greater height loss during middle age may be at higher risk of death, Swedish research suggests.
Scientists previously found that shorter people...
Twice-yearly inclisiran injections as alternative to daily statins in NHS plan
Inclisiran, administered through twice-yearly injections, saw cholesterol levels fall by half in an Imperial College London study. Under a British NHS plan, the gene-silencing...
New ESC and EACTS valvular disease guidelines
In line with recent US recommendations, the newest European guidelines favour a wider pool of patients eligible for surgical and transcatheter interventions for valvular...
Stroke risk 7x higher in sedentary under-60s — Large Canadian study
Adults under 60 who spend eight or more house a day sitting have a sevenfold higher risk of stroke compared with those who spent...
Evidence of vitamin K benefits for heart health — 23-year Australia study
Researchers at Australia’s New Edith Cowan University (ECU) found that people who eat a diet rich in vitamin K have up to a 34%...
Association between womenʼs middle-age height loss and greater risk of death
Women who experience greater height loss during middle age may be at higher risk of death, Swedish research suggests.
Scientists previously found that shorter people...
Moderate drinking not associated with increased heart or death risk — Large UK analysis
Those drinking up to 62 grams of alcohol per day – equivalent to two glasses of wine – did not have an increased risk...
Single-shot abelacimab cuts venous thromboembolism risk in knee surgery
A single abelacimab injection prevents blood clots for up to a month after surgery, reducing risk by about 80% compared with enoxaparin, without increasing...
Mortality benefit to adding rivaroxaban to aspirin in coronary artery disease — COMPASS trial
Combining rivaroxaban with aspirin may help certain patients with coronary artery disease (CAD) or peripheral artery disease (PAD) live longer than they would with...
Ramadan fasting and cardiovascular disease — Newham University recommendations
Expert consensus says Muslim patients at high cardiovascular risk should not observe strict fasting during Ramadan, writes MedicalBrief.
While recommendations on ‘safeʼ fasting exist for...
Final SPRINT study confirms benefits of aggressive BP management
Final results from the landmark SPRINT study confirm that aggressive blood pressure (BP) management, targeting a systolic blood pressure (SBP) below 120 mm Hg,...
Experts urge action to reduce global burden of cardiovascular disease in women
Urgent action is needed to improve care and prevention, fill knowledge gaps and increase awareness about cardiovascular disease in women, according to a report...
Baby Aspirin on par with full-dose for cardiovascular disease
A large landmark study found that low-dose and regular-strength aspirin is equally safe and effective for preventing additional heart problems in people who already...
Omega-3 supplementation linked with atrial fibrillation risk — Meta-analysis
Omega-3 supplements are associated with an increased likelihood of developing atrial fibrillation in people with high blood lipids, a meta-analysis of randomised control trials...
Lowering BP significantly reduces CV risk even at normal levels
Even in those with normal or only mildly elevated blood pressure (BP), anti-hypertensive medication lowering of BP protects against future cardiovascular (CV) events, found...
'Striking' association of cardiovascular risk factors with late-life cognitive decline
An increase in risk factors for cardiovascular disease (CVD) during young adulthood is associated with cognitive decline in late life, a US data analysis...
CVD the leading cause of death in patients with type 2 diabetes
Cardiovascular disease (CVD) was the leading cause of death among the over 16,000 patients with type 2 diabetes (T2DM) who were enrolled in the...
Cancer survivors face elevated risk of cardiovascular disease over 10 years
A study has found that about 35% of Americans with a cancer history had an elevated risk of atherosclerotic cardiovascular disease (ASCVD) in the...
Stroke risk higher than expected among COVID-19 patients
Research found patients hospitalized with COVID-19 had a higher risk of stroke, compared with patients who had similar infectious conditions such as influenza and...
Statins found to have no effect on muscle pain in placebo trial
A study has found no overall effect of statins on the frequency or severity of muscle symptoms compared with placebo in people who had...
Sex differences in 'normal' blood pressure and associated CVD risk
Women have a lower "normal" blood pressure range compared to men and that this is linked to risk for each specific cardiovascular disease (CVD)...
Meta-analysis: No cardiovascular benefits to dietary supplements except vitamin B
No cardiovascular or mortality effects were seen with multivitamins, vitamin D, calcium, or vitamin C in a meta-analysis incorporating 156 randomised controlled trials and...
Polypill plus aspirin reduces incidence of cardiovascular events by 31% — TIPS-3
Researchers have found that combined treatment with a polypill plus aspirin led to a 31% lower incidence of cardiovascular events than did placebo among...
Inter-arm difference in BP robustly linked to greater early death risk
Robust evidence from a large meta-analysis published in Hypertension confirms that a difference in blood pressure readings between arms is linked to greater risk...
Hypertension may speed cognitive decline, irrespective of age or duration
Memory, concentration and other cognitive functions decline faster among middle-aged and older adults who have high blood pressure than those who do not, while...
Even low-dose steroid treatments substantially increase CVD risk
While high doses of steroids are known to increase the risk of cardiovascular disease (CVD), the impact of lower doses is unknown, a Leeds...
Large trial produces 'best evidence' of aspirin benefits in reducing CVD risk
Aspirin added significantly to the benefits of a low-cost ‘polypill’ approach for primary prevention of cardiovascular disease in an intermediate-risk population, the TIPS-3 study...
Omega-3s humbled by corn oil placebo in two trials
Low-dose omega-3 fatty acids offered no cardiovascular benefit over corn oil placebo in two randomised trials of high-risk patients, resurfacing old questions about why...
Aspirin use best for those with high coronary calcium, low risk of bleeding
An X-ray test commonly used to assess hardening of the arteries could help doctors decide whether the benefits of taking aspirin to prevent a...
High-flavanol diet associated with lower blood pressure
In one of the largest studies to use nutritional biomarkers to estimate intake of bioactive food compounds, a UK study published in Nature found a...
Arthritis therapy link to cardiovascular disease improvements
A two-year study by the University of Leeds has for the first-time linked treatment for initial signs of rheumatoid arthritis with improvements in vascular...
Doubt cast on targeting 'bad' cholesterol to curb heart disease risk
Setting targets for ‘bad’ (LDL) cholesterol levels to ward off heart disease and death in those at risk might seem intuitive, but a systematic...
Mortality risk increases in older patients with low BP
A large-scale study led by the University of Exeter and funded by NIHR, analysed 415,980 electronic medical records of older adults in England. The...
Researchers question new guidelines on aspirin in primary prevention
There has been considerable confusion from three large-scale randomised trials of aspirin in high risk primary prevention subjects, leaving doctors understandably confused about whether...
Cocoa may improve walking in people with peripheral artery disease — small study
In a small study of 44 peripheral artery disease patients over age 60, those who drank a beverage containing flavanol-rich cocoa three times a...
Large data analysis links cholesterol levels to heart disease and stroke risk
An observational and modelling study which used individual-level data from almost 400,000 people extends existing research because it suggests that increasing levels of non-HDL...
Landmark study highlights importance of cholesterol monitoring of young adults
Adults as young as 25, not only older people, need to know their “bad cholesterol” (non-HDL) levels so they can change their lifestyle or...
Canadian review: Aspirin not recommended for those not at risk of CVD
Those who've never had a heart attack or stroke, should not be taking daily aspirin to prevent them, found a Canadian review of ...
New NICE hypertension guidelines a 'pragmatic compromise’ — The Lancet
The latest UK National Institute for Health and Clinical Excellence (NICE) guidelines on antihypertensives "should be welcomed" as "a pragmatic compromise", writes The Lancet in an...