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Schools have not developed into hotspots — ongoing German study

The medical faculty of the TU Dresden and Dresden University Hospital Carl Gustav Carus started a study on the spread of the SARS-CoV-2 virus...

Prevalence of SARS-CoV-2 infection in Spain: Nationwide, population-based sero-epidemiological study

Summary Background: Spain is one of the European countries most affected by the COVID-19 pandemic. Serological surveys are a valuable tool to assess the extent...

SARS-CoV-2 seroprevalence in COVID-19 hotspots – Lancet comment

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has surprised the world with its range of disease manifestations, from asymptomatic infection to critical illness leading...

National Institute of Allergy and Infectious Diseases-sponsored phase 1 trial tested mRNA vaccine

An investigational vaccine designed to protect against COVID-19 was generally well tolerated and prompted neutralising activity in healthy adults, according to interim results. The...

Smell tests should be part of routine COVID-19 screenings — STAT News

Temperature checks could well join the long list of fumbled responses to the pandemic, from the testing debacle to federal officials’ about-face on masks,...

Clinical and demographic risk factors for COVID-19 deaths in 17 million NHS patients

Risk factors associated with COVID-19 death, based on analyses of full pseudonymized health records of 17m adults in England, are reported in a study...

Urgent need to mitigate surgical risk during pandemic

A large, 24-nation cohort study reporting post-operative outcomes in COVID-19 of post elective and emergency surgical patients found poor outcomes exceeding those seen in most...

COVID-19 herd immunity may be unachievable — Spanish study of 61,000 people

Spain's large-scale study on the coronavirus indicates just 5% of its population has developed antibodies, strengthening evidence that a so-called herd immunity to COVID-19...

NICD report: Epidemiology and clinical characteristics of COVID-19 in SA children

According to a National Institute of Communicable Diseases (NICD) report, children made up less than 7% of all reported COVID-19 cases in South Africa and...

Groote Schuur doctors on benefits of high-flow nasal oxygen — Spotlight report

Spotlight reports that doctors at two of the Western Cape’s most impacted COVID-19 hospitals say they have seen positive outcomes from using high-flow nasal...

Problematic response of the elderly to COVID-19 — 27-country survey

Survey results from 27 countries suggest that, despite their increased risk of severe illness due to COVID-19, elderly people are not more willing to...

WHO discontinues hydroxychloroquine and lopinavir/ritonavir treatment arms for COVID-19

The World Health Organisation (WHO) has announced that it has accepted the recommendation from the Solidarity Trial’s International Steering Committee to discontinue the trial’s...

JAMA study: 35% of excess US deaths tied to causes other than COVID-19

Since COVID-19’s spread to the US earlier this year, death rates in the US have risen significantly. But deaths attributed to COVID-19 only account...

Immunity to COVID-19 may be higher than tests have shown — Karolinska Institutet

Research from Karolinska Institutet and Karolinska University Hospital shows that many people with mild or asymptomatic COVID-19 demonstrate so-called T-cell-mediated immunity to the new...

Outbreak in Italian town of Vo shows importance of asymptomatic cases — Nature

A study of COVID-19 in the quarantined Italian town of Vò, where most of the population was tested, reveals the importance of asymptomatic cases....

Small Spanish study supports link between coronavirus and COVID toes

There's considerable controversy over whether "COVID toes” – red sores or lesions on the feet and hands in children and young adults – are...

SARS-CoV-2 infection associated with platelet hyper-reactivity — small Utah study

Changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who...

Infectious Diseases Society of America updates COVID-19 management guidelines

The Infectious Diseases Society of America updated the treatment portion of its COVID-19 management guidelines, making more specific recommendations for medications. “Back in April...

UK's NICE review not recommending vitamin D to reduce risk of COVID-19

A UK National Institute for Health and Care Excellence (NICE) rapid evidence review has failed to find data to support using vitamin D supplements...

Coronavirus vaccine likely in 12 months — ARV drug co-inventor Larry Corey

Unlike HIV, the coronavirus is more open to the development of a vaccine and one should be within the grasp of modern science by...

HIV drug combo shows no benefit in treating COVID-19 patients — Oxford trial

A combination of antiretroviral drugs used to treat HIV had no beneficial effect in patients hospitalised with COVID-19 in a large-scale randomised trial. Reuters...

Survivors need PTSD screening — COVID Trauma Response Working Group guidelines

Patients affected by COVID-19 need to be urgently screened for post-traumatic stress disorder (PTSD), and receive regular check-ups for at least a year. The...

Brain complications in patients with COVID-19 — First UK nationwide surveillance study

Researchers at the University of Liverpool have led the first nationwide surveillance study of the neurological complications of COVID-19. A study of 153 patients...

UK's new rules: No communal dancing nor screaming on rollercoasters

No "communal dancing", singing or laughing. No screaming on rollercoasters or making a cuppa for the plumber. The UK's new post-lockdown rules change daily...

Clear signs of brain injury with severe COVID-19 — Small Swedish study

Certain patients who receive hospital care for coronavirus infection (COVID-19) exhibit clinical and neuro-chemical signs of brain injury, a University of Gothenburg study shows....

Critically ill COVID-19 patients 10x more likely to develop cardiac arrhythmias

Patients with COVID-19 who were admitted to an intensive care unit were 10 times more likely than other hospitalised COVID-19 patients to suffer cardiac...

Higher rates of severe COVID-19 in BAME populations remain unexplained

Higher rates of severe COVID-19 infections in Black, Asian and Minority Ethnic (BAME) populations are not explained by socioeconomic or behavioural factors, cardiovascular disease...

Two US research reports on multi-system inflammation syndrome in children

Two US research groups have reported finding nearly 300 cases of an alarming apparent side effect of COVID-19 in children, a condition called multisystem...

Children with multi-system inflammatory syndrome post-COVID-19 — Small UK study

In recent weeks, a multi-system hyper-inflammatory condition has emerged in children in association with prior exposure or infection to SARS-CoV-2. A new case series...

COVID-19 generally a mild disease in children — Analysis of 582 European patients

Children with COVID-19 generally experience a mild disease and fatalities are very rare, according to a study of 582 patients from across Europe. The...

Far-UVC light safely kills airborne coronaviruses — Columbia University

More than 99.9% of seasonal coronaviruses present in airborne droplets were killed when exposed to a particular wavelength of ultraviolet light that is safe...

Leeds research review confirms WHO's 'classic' symptoms of COVID-19

Persistent cough and fever have been confirmed as the most prevalent symptoms associated with COVID-19, according to a major review of the scientific literature....

Black men in England and Wales 3x more likely to die from COVID-19 — National Office of Statistics

Black men in England and Wales are three times more likely to die from COVID-19 than white men, The Guardian reports that the Office...

How COVID-19 affects paediatric patients — China study in PLOS Medicine

New insights into the clinical and epidemiological characteristics of paediatric patients with coronavirus disease 2019 (COVID-19) could facilitate early identification and intervention in suspected...

SA doctor experiences rare spinal paralysis from COVID-19

Initially, COVID-19 had not made him that ill. News24 reports that on one day, he struggled with a nasal drip, a sore throat on...

FDA revokes emergency use authorisation for chloroquine phosphate and hydroxychloroquine sulfate

The US Food and Drug Administration (FDA) has revoked the emergency use authorisation (EUA) that allowed for chloroquine phosphate and hydroxychloroquine sulfate donated to...

Comorbidities increase death risk twelvefold — US Centres for Disease Control

People with chronic health conditions such as heart disease and diabetes were hospitalised six times more often than otherwise healthy individuals infected with the...

Up to 45% of covid infections may be asymptomatic — Scripps analysis

An extraordinary percentage of people infected by the virus behind the ongoing deadly COVID-19 pandemic never show symptoms of the disease, according to the...

Age-dependent effects in COVID-19 transmission and control — London School of Hygiene & Tropical Medicine

People under 20 years of age are approximately half as susceptible to COVID-19 as are people 20 years of age and older, according to...

COVID-19 may trigger new diabetes — NEJM expert letter

Emerging evidence suggests that COVID-19 may actually trigger the onset of diabetes in healthy people and also cause severe complications of pre-existing diabetes. A...