HomeHIV/AIDS
HIV/AIDS
Observed rate of viral failure in two regimens
"The observed rate of viral failure during follow-up was lower among people living with HIV initiating dolutegravir-based vs darunavir-based regimens in routine clinical care...
Regimen change associated with weight gain
According to results of a study presented at IDWeek 2017, an increase in body weight is common in HIV patients who are switched from...
Improved renal and bone safety from FTC/TAF regimen in black adults
Among HIV-infected, virologically suppressed black adults, emtricitabine/tenofovir alafenamide (FTC/TAF) showed improvements in renal and bone safety compared to emtricitabine/tenofovir disoproxil fumarate (FTC/TDF), according to...
Critical to screen for depression in people with HIV in SSA
Since depression can have deleterious consequences on the lives of people liviing with HIV/AIDS, it is critical to encourage its screening and management, integrating...
Impact of behavioural factors on health and survival of HIV-HCV patients
Novel five-year study highlights importance of behaviours such as coffee drinking and not smoking on health and survival of HIV and HCV infected patients,...
HIV rates for the over-50s climbing in Europe
HIV rates are climbing in the over-50s in the UK and across Europe, while the rate of new infections among younger people is dropping,...
Engineered antibody that attacks HIV strains an 'exciting breakthrough'
Scientists have engineered an antibody that attacks 99% of HIV strains and can prevent infection in primates, reports BBC News.
Scientists from Sanofi, the Vaccine...
Once daily fixed dose of ART safe in children
A once-daily fixed-dose coformulation of elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide was safe and efficacious in children with HIV, found a study led by...
Period when MSM are potentially infectious is falling significantly
The period during which HIV-positive men who have sex with men (MSM) are potentially infectious fell significantly between 2007 and 2016, investigators from Australia...
BHIVA challenges recommendation on ART for HIV+ pregnant women
The British HIV Association (BHIVA) has taken issue with a BMJ article regarding the PROMISE trial that led to a recommendation on the use...
Smokers with HIV 10x more likely to die from lung cancer
People living with HIV who adhere to antiretroviral therapy but smoke cigarettes are around 10 times more likely to die from lung cancer than...
Treating chronic pain in HIV patients
Because ongoing pain is a significant problem that affects 39% to 85% of people living with HIV, everyone with the infection should be assessed...
Factors in failing to start ART
With the goal of preventing HIV transmission and disease progression, US federal guidelines since early 2012 have suggested everyone who tests HIV positive should...
Study looks at US youth transitioning to adult HIV care
While a number of qualitative studies have been completed looking at the specific challenges relating to HIV care transition for young people living with...
New recommendations on ARVs for pregnant women living with HIV
New recommendations on antiretroviral drugs for pregnant women living with HIV can help women make more informed choices about benefits and harms, says...
Dolutegravir may link to serious depression
Severe depression may be a side-effect of treatment with the anti-HIV drug dolutegravir, according to clinicians from The Netherlands , who report two cases of...
Morning drug-taking helps to reduce insomnia
Italian doctors say that sleeplessness after taking the integrase inhibitor dolutegravir occurred much less often when their patients took their dose of the drug...
Better retention for HIV patients who have six-month clinic visits
Patients receiving care for HIV who were scheduled for clinic visits every six months were less likely to show up late, miss visits, have...
Electronic update of HIV prevention and treatment guidelines
The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV Infected Adults and Adolescents document have been published in an electronic format...
Abstinence-only-until-marriage programmes found ineffective
Two scientific review papers show that abstinence-only-until-marriage programmes and policies in the US are ineffective as they do not delay sexual initiation or reduce...
Intervention with HIV+ parents increases disclosure to children
Ground breaking research led by a team of SA scientists proves that, given the right support, HIV-positive parents will disclose their status to...
Maraviroc for HIV prevention safe and well tolerated in women
Pre-exposure prophylaxis regimens containing maraviroc were safe and well-tolerated in women at risk for HIV infection compared with emtricitabine-tenofovir disoproxil fumarate, according to results...
Combination of darunavir/ritonavir and lamivudine is as efficacious as triple therapy
Recent findings demonstrated that dual therapy with darunavir/ritonavir and lamivudine was non-inferior to triple therapy with darunavir/ritonavir plus tenofovir disoproxil fumarate and emtricitabine or...
Vit D supplementation improves lumbar spine bone mineral density
Monthly doses of vitamin D increased bone density in HIV-infected youth who were receiving Viread as part of their combination antiretroviral therapy, or cART,...
HIV drug resistance in more than half of young African children
Approximately 54% of young children with HIV surveyed in Africa had resistance to one or more antiretroviral drugs, an analysis found.
The prevalence of HIV...
Peripheral artery disease more common with lower CD4 counts
Peripheral artery disease occurs more frequently in people with HIV who have CD4 cell counts below 500, regardless of whether they smoke or have...
Switch from efavirenz delivers benefits in HIV+ fatty liver disease
Switching to raltegravir from efavirenz is associated with significant improvements in liver steatosis for HIV-positive people with non-alcoholic fatty liver disease, Spanish investigators report.
The...
VMMC cuts female HIV risk by as much as 30%
Ground-breaking research presented at the recent International AIDS Society Conference on HIV Science IAS 2017 in Paris, suggests that voluntary medical male circumcision (VMMC)...
Boosted darunavir plus lamivudine matches three-drug regimen
A combination of darunavir/ritonavir and lamivudine was just as effective as the same combination plus tenofovir, according to 24-week results of the ANDES study,...
Single measures of viral load not effective for assessing suppression
The percentage of HIV-positive individuals with durable viral suppression may be overestimated when calculated by single measures of viral load, Healio reports a study...
First protease inhibitor combination pill maintains viral suppression
The first once-daily single-tablet regimen containing a protease inhibitor maintained viral suppression in almost everyone who switched after achieving undetectable HIV RNA on a...
ART administered intramuscularly as effective as oral Tx
Antiretroviral therapy (ART) intramuscularly administered may have the same effectiveness as current oral treatments. This is the main conclusion of the Phase II clinical...
HIV stillbirth rate is double that of general UK population
The stillbirth rate among women living with HIV in the UK and Ireland from 2007 to 2015 was more than twice that of the...
Factors beyond ART play role in the health of sub-Saharan HIV+ adolescents
Adolescents who acquired HIV perinatally were less likely to die, grew faster and had better immune restoration on treatment if they lived in upper-middle...
To be successful, multi-month prescribing needs fine tuning
Shifts to less frequent clinic visits and medication pick-ups to free up healthcare resources and make life easier for people living with HIV are...
Improved access to antifungal flucytosine is critical
Urgent action is needed to improve access to the antifungal drug flucytosine, say investigators, following the presentation of the results of a trial showing...
Self-testing improves uptake among sex workers
A year ago there was virtually no evidence on the acceptability and feasibility of HIV self-testing in female sex workers, but a series of...
Low-cost drugs package saves lives of people starting Tx late
Treating people who start HIV treatment late with a package of low-cost drugs to prevent serious infections saves three lives for every 100 people...
High BMI, diabetes and elevated lipids with HIV increases NAFLD risk
Over a third of people with HIV have non-alcoholic fatty liver disease (NAFLD) in the absence of hepatitis B or C, according to the...
Most people on ART will not experience viral rebound
British investigators have determined that a substantial proportion of people with HIV who are taking antiretroviral therapy (ART) will not experience viral rebound during...