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Alarming surge in resistance to crucial HIV drugs uncovered
Health authorities have uncovered an alarming surge in resistance to crucial HIV drugs. Surveys by the World Health Organisation (WHO) reveal that, in the...
How poverty, violence and inequality play a part in HIV risk
Andrew Gibbs, senior specialist scientist: Gender and Health Research Unit, South African Medical Research Council writes in The Conversation:
“It’s obvious that men’s practices and...
Australia reports considerable reduction in new HIV diagnoses among MSM
In Australia the annual HIV diagnosis rate declined by nearly 25% over five years and hit a low in 2018 not seen since 2001....
CRISPR technology used to eliminate HIV virus in living mice
Researchers say they’re one step closer to finding a potential cure for HIV after successfully eliminating the virus in living mice for the first...
Major TB reduction impossible without expansion of ART coverage
Tuberculosis incidence in sub-Saharan Africa is falling too slowly to meet global targets of an 80% reduction by 2030, and where incidence is falling,...
Older, anonymous partners pose more HIV infection risk for adolescent girls in SA
South African research has found that adolescent girls and young women (aged 13-23) were more than twice as likely to be infected with HIV...
Preschools must do more to support children living with HIV
Thanks to antiretroviral therapy, children living with HIV are likely to live much longer than they would without treatment. They will go to school...
No neuro-developmental harm to uninfected infants from ARVs
In the first five years of life the neurological development of HIV-exposed but uninfected infants, exposed to maternal antiretrovirals before and after birth and...
Invasive cervical cancer rates high in women living with HIV in Africa and Latin America
A study has found that rates of invasive cervical cancer (ICC) are particularly high in women living with HIV in South Africa or Latin...
PrEP reduces HIV infections by over 95% in US 'real world' study
A study of people prescribed pre-exposure prophylaxis (PrEP) over a four-year period at a large centre in Los Angeles has found that HIV incidence...
Injectable contraceptive does not raise HIV risk — large trial
A large clinical research study conducted in four African countries found no significant difference in risk of HIV infection among women using one of...
Mapping intervention strategies to improving men's HIV testing
HIV testing serves as a critical gateway for linkage and retention to care services. This is also key to improving the health and well-being...
Three studies nudging the frontiers of HIV prevention
There are an estimated 5,000 new HIV transmissions every day. About 70% of the 37m people living with HIV globally are in sub-Saharan Africa....
Following Tx interruption, most children recover immunologically
Just over one in ten (12%) children and adolescents living with HIV in Europe and Thailand take a break from antiretroviral treatment, usually as...
Higher drop-out rates at community-based adherence clubs
Antiretroviral treatment adherence club drop-out rates were significantly higher for people attending community-based clubs compared to clinic-based clubs, reveals a study from South Africa....
Testing for HIV has doubled diagnosis rates — CDC
Tracing and offering HIV tests to exposed partners and children of people living with the virus led to twice the rate of positive tests...
Preventing drug-induced liver injury in patients with HIV
With an estimated annual incidence rate of 13.9 to 24 per 100,000 inhabitants, drug-induced liver injury (DILI) the leading cause of acute liver failure...
Churches can help increase HIV testing in South African men
An HIV testing campaign conducted within South African churches successfully recruited 43% of the congregation for HIV testing on campaign days and was most...
Systematic review on what works against self-stigma
A systematic review of whether different interventions helped to overcome self-stigma in people in African and Asian countries who are living with or at...
Stepped care programme helps to reduce drinking in those with HIV
People with HIV who drink too much were more likely to reduce drinking after undergoing an approach to care known as integrated stepped alcohol...
New HIV map offers most detailed look yet at the epidemic
The UN has set a goal of ending the global HIV/Aids epidemic by 2030. The tide is slowly turning in south-eastern Africa – which...
Point-of-care technology for early infant HIV diagnosis
Point-of-care testing for early infant HIV diagnosis is highly effective in reducing turnaround time for HIV test results, enabling earlier antiretroviral treatment initiation in...
'Undetectable equals untransmittable' should be basic HIV knowledge
Further evidence that taking anti-HIV drugs stops gay men passing on the virus to sexual partners has been called a "powerful message" which needs...
HIV prevention strategies used by serodiscordant couples
Two years ago, the Opposites Attract study found no transmissions between 343 regular gay couples of differing HIV status where the HIV-positive partner had...
Why the uptake of lopinavir/ritonavir pellets for children has been slow
Lopinavir/ritonavir (LPV/r) oral pellets and oral granules for infants and young children living with HIV have proven advantages in terms of efficacy and tolerability...
Multi-month scripting of ART at scale pays off
As ministries of health and their partners move to scale up differentiated service delivery (DSD) for HIV treatment, one approach is taking the spotlight....
Heating IDPE before injection may be a harm reduction strategy
Studies from Lawson Health Research Institute and Western University have found for the first time that HIV can be transmitted through the sharing of...
Scientists identify rare, paradoxical response to ART
Antiretroviral therapy (ART) is usually very effective at suppressing HIV in the body, allowing a person's immune system to recover by preventing the virus...
Rifapentine plus isoniazid non-inferior to isoniazid in HIV related TB
For prevention of tuberculosis (TB) in people with HIV, a single month regimen of rifapentine plus isoniazid was non-inferior to 9 months of isoniazid...
When PrEP should be offered as a 'matter of urgency'
PrEP (pre-exposure prophylaxis) should be offered as a matter of urgency to gay men with a recent STI or multiple condomless partners, found an...
The complicated issue of weight gain with new ARVs
Professor Francois Venter and Dr Simiso Sokhela write in a Spotlight report: “South Africa’s next big shift in our antiretroviral programme is to replace...
First year of PrEP in Scotland: more users than expected, few dropouts, few HIV infections
The report on the first year of the implementation of pre-exposure prophylaxis (PrEP) through the National Health Service (NHS) in Scotland concludes: “Year one has...
Clusters of co-morbidities in those with HIV show major non-HIV medical needs
Most health problems in people living with HIV in two large cohorts can be classified in six clusters, with cardiovascular disease, metabolic problems, sexually...
Study argues against uniform policy of avoiding dolutegravir in women of child-bearing potential
Although neural tube defect risks may be higher with dolutegravir than efavirenz, dolutegravir will lead to many fewer deaths among women, as well as...
Individual advice from dietitian helps people with HIV manage diabetes risk
Rates of diabetes are higher in people living with HIV than in the general population, but individualised lifestyle advice from a dietitian led to...
Effect of depression on cognitive function in people living with HIV
Compared with patients without HIV, the poorer cognitive performance of people living with HIV (PLWHIV) was partly mediated by a higher prevalence of depressive...
Impact of older ARVs on fat redistribution and CVD risk may be irreversible
Fat redistribution in people with HIV who have ever taken thymidine analogues and/or didanosine (TA/ddI) can persist through time, while increasing cardiovascular risk factors,...
Urine test can provide accurate point-of-care results about PrEP adherence
A point-of-care urine test can accurately determine if a person is adherent to tenofovir-based pre-exposure prophylaxis (PrEP), according to researchers at University of California...
Tests identify HIV's final redoubt
The dynamics of HIV proliferation in the viral reservoir might be the explanation for why viral load fails to become undetectable, especially when adherence...
Healthcare providers challenged on failure to inform HIV patients
Healthcare providers should inform all patients with HIV they cannot transmit HIV to a sexual partner when their viral load is undetectable, argue the...