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Oncology
NHS pilots simple blood test that screens for 50 types of cancer
A simple blood test that can detect more than 50 types of cancer in asymptomatic patients is accurate enough to be rolled out as...
‘Potential new standard’ in high-risk kidney cancer — KEYNOTE-564 trial
Single-agent immune checkpoint inhibition after surgery reduced the risk of disease recurrence or death in patients with high-risk clear cell renal cell carcinoma (RCC),...
Trials stopped early as benefits shown for olaparib in breast cancer
Women with hereditary breast cancer, triggered by the BRCA1 or BRCA2 genes, stand a better chance of survival following successful trials of a drug...
PARP inhibitor shrinks tumours in pancreatic cancer with mutations
More than two-thirds of pancreatic cancer patients harbouring genetic mutations saw their tumour stop growing or shrink substantially after being switched from intensive chemotherapy...
Sugary drinks associated with increased risk of colorectal cancer in women
Heavy consumption of sugary drinks during adolescence and adulthood is associated with an increased risk of developing colorectal cancer in women under age 50,...
An epidemiological insight into HPV status and prognostic gene mutations in head and neck cancer
A study release from Clarivate:
Summary
Since human papilloma virus (HPV) infection is related to sexual practices and HPV positive head and neck cancers (HNCs), particularly...
Immunotherapy combination shows early promise in glioblastoma
Immunotherapy together with an experimental cancer drug could offer a new way of treating some patients with aggressive brain cancers, promising early results from...
Bariatric surgery significantly cuts cancer risk in severely obese NAFLD patients
Bariatric surgery can significantly reduce the risk of cancer – and especially obesity-related cancers – by as much as half in certain individuals, according...
CT scan catches 70% of lung cancers at early stage — SUMMIT study
Giving smokers and ex-smokers a CT scan uncovers cancerous lung tumours when they are at an early enough stage so they can still be...
MRI improves detection of clinically significant prostate cancer — IP1-PROSTAGRAM study
MRI improved detection of clinically significant prostate cancer without increasing overdiagnosis compared with PSA testing, according to a prospective, population-based, blinded cohort study. The...
Pre-diagnosis aspirin use may lower colorectal cancer mortality — American Cancer Society
A study finds that long-term aspirin use before a diagnosis of colorectal cancer (CRC) may be associated with lower CRC-specific mortality, found an American...
Faecal transplant boosts immunotherapy in advanced melanoma
Researchers at UPMC Hillman Cancer Centre, the University of Pittsburgh School of Medicine, the National Cancer Institute (NCI), Oregon State University and the National...
Earlier-age daily aspirin linked to lower incidence of colorectal cancer in aged
There is substantial evidence that a daily aspirin can reduce risk of colorectal cancer in adults up to age 70. An a large data...
Better post-surgery care would 'dramatically improve' cancer survival — 82-country study
Patients’ chances of survival after cancer surgery is strongly linked with the standard of post-operation hospital care, with patients in low-and lower-middle-income countries were...
Statins may protect the heart from chemotherapy in early breast cancer
Statins may protect women's hearts from damage caused during chemotherapy for early-stage breast cancer, according to a cohort study.
"Two types of cancer medications,...
Many women could safely skip breast cancer chemo — RxPONDER Trial
More women with early-stage breast cancer may safely forgo chemotherapy, suggests an interim analysis that had a median follow-up of five years of the...
UK to trial blood test that detects more than 50 types of cancer
A novel blood test that can detect more than 50 types of cancer, often before symptoms show, is to be trialled by the UK's...
Lorlatinib a potential first-line option for ALK-positive lung cancer patients
Lung cancer patients with a specific genetic alteration lived longer and were protected against metastasis to the brain when treated early with the drug...
Small personalised cancer vaccine clinical trial to expand following promising early results
A clinical trial at the University of Arizona Health Sciences designed to study the safety and effectiveness of a personalised cancer vaccine in combination...
A month's delay in cancer treatment may raise death risk up to 13%
People whose treatment for cancer is delayed by even one month have 6% to 13% higher risk of dying – a risk that keeps...
Two immune therapy studies show promise in advanced cervical cancer
Preliminary results from two independent, phase II clinical trials investigating a new PD-1 (programmed cell death protein 1)-based immune therapy for metastatic cervical cancer...
Colorectal cancer prevention: BMJ evidence review of 80 meta-analyses
An evidence review in The BMJ examines 80 meta-analyses of interventional and observational studies of colorectal cancer (CRC) prevention using medications, vitamins, supplements and...
Tagriso shown to slow spread of EGFR gene mutation brain metastases
AstraZeneca’s top-selling drug Tagrisso has been shown to slow the spread of a certain type of lung cancer to the brain when diagnosed at...
Combining two precision medicines to treat drug-resistant cancers
Launching a dual-pronged attack on tumours using a combination of two precision medicines could treat patients with multiple common cancers, a clinical trial shows....
Use of permanent hair dye and cancer risk
Women who use permanent hair dye products to colour their hair at home do not experience greater risk of most cancers or greater cancer...
Single dose radiotherapy effective in treating breast cancer
A pioneering breast cancer therapy developed by University College London (UCL) clinicians, which requires just one shot of radiotherapy rather than conventional weeks-long treatment,...
Breast screening women in their 40s to save lives – long-term UK study
A 23-year follow-up of a large UK trial found that screening women aged 40-49 led to a substantial and significant 25% reduction in breast...
Higher end of normal blood platelet count may indicate cancer
Blood platelet counts at the higher end of normal suggest a high risk of cancer in men aged 60 or over, and should be...
Simple urine test could improve detection of adrenal cancer
Using a simple urine test alongside routine imaging for patients with adrenal masses could speed up adrenal cancer diagnosis, improving patient's prognosis and reducing...
Fasting diet may boost hormone drugs in breast cancer therapy
A University of Southern California-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat...
Blood test may detect 5 cancers up to 4 years earlier in asymptomatic patients
A non-invasive blood test, which could be used as a potential tool for the early detection of five common types of cancer up to...
Vitamin D may help reduce colitis risk during immunotherapy
Taking vitamin D supplements might reduce the risk of colitis in patients receiving immune checkpoint inhibitors to treat their cancer, found a US study.
Immune...
New blood test for cancer up to 10x more sensitive
A new method of analysing cancer patients' blood for evidence of the disease could be up to ten times more sensitive than previous methods...
Sedentary behaviour independently predicts cancer mortality
In the first study to look at objective measures of sedentary behaviour and cancer mortality, researchers from The University of Texas MD Anderson Cancer...
Nicotine promotes metastasis of lung cancer to the brain
Among people who have the most common type of lung cancer, up to 40% develop metastatic brain tumours, with an average survival time of...
World-first: Saliva test detects a hidden throat cancer
A simple saliva test developed by Australian biomedical scientists has detected early throat cancer in a person who had no symptom and no clinical...
Microcytosis in men linked to more than double the risk of cancer
Having abnormally small red blood cells – a condition known as microcytosis – is linked to more than double the risk of several cancers...
Major trial shows breast cancer drug can hit prostate cancer Achilles heel
Olaparib, a pill lacking the side effects of chemotherapy, can target an Achilles heel in prostate cancers with a weakness in their ability to...
Aspirin linked to reduction in risk of several cancers of the digestive tract
The largest and most comprehensive analysis to date of the link between aspirin and digestive tract cancers has found reductions in the risk of...
New blood test accurately detects more than 50 types of cancer
In a study involving thousands of participants, a new blood test detected more than 50 types of cancer as well as their location within...