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Oncology
Exercise may alleviate ‘chemo brain’ in breast cancer — Washington University study
Regular exercise may help lessen “chemo brain” among women being treated for breast cancer, according to a large-scale study of the associations between physical...
Adavosertib may delay tumour regrowth in inoperable metastatic colorectal cancer
Adavosertib, taken as a daily pill, may delay tumour regrowth among patients with an aggressive sub-type of inoperable metastatic colorectal cancer, found a UK...
ESMO 2021: Highly promising results against breast and ovarian cancer
AstraZeneca’s Enhertu demonstrated a 72% reduction in the risk of disease progression or death in HER2-positive metastatic breast cancer according to trial results presented...
Increased colon cancer risk extends to second- and third-degree relatives
Having second- or third-degree relatives with colorectal cancer significantly increases the risk of developing the disease, found a study in Cancer Epidemiology. Early screening...
Antibiotic use linked to increased risk of colon cancer — Swedish Colorectal Cancer Registry
There is a clear link between taking antibiotics for more than six months and an increased risk of developing colon cancer within the next...
Antibiotic use linked to increased risk of colon cancer — large Swedish analysis
There is a clear link between taking antibiotics and an increased risk of developing colon cancer within the next five to 19 years, found...
Statins may significantly improve survival in triple-negative breast cancer
A significant association was found between cholesterol-lowering drugs, commonly known as statins, and survival rates of triple-negative breast cancer patients, found a study led...
High Intensity Training regimen may inhibit prostate cancer growth — ERASE trial
Rigorous exercise not only boosted cardiorespiratory fitness, but also improved indicators of prostate cancer biochemical progression in patients undergoing active surveillance, according to results...
Statins may significantly improve survival in triple-negative breast cancer
A significant association was found between cholesterol-lowering drugs, commonly known as statins, and survival rates of triple-negative breast cancer patients, found a study led...
Vitamin D deficiency from inadequate sunlight may increase colorectal cancer risk
Inadequate exposure to UVB light from the sun may be associated with an increased risk of colorectal cancer, particularly in older age groups, according...
Hysterectomy plus chemo improves metastatic uterine cancer survival
Total abdominal hysterectomy (TAH), in addition to chemotherapy, significantly improved overall survival (OS) in patients with newly diagnosed uterine cancer and distant metastases, a...
Cancer Research UK: Progress at detecting glioma through urine
Cancer Research UK scientists report “very promising results” at detecting for the first time signs of glioma through urine, according to a study in...
NHS pilots simple blood test that screens for 50 types of cancer
A simple blood test that can detect more than 50 types of cancer in asymptomatic patients is accurate enough to be rolled out as...
‘Potential new standard’ in high-risk kidney cancer — KEYNOTE-564 trial
Single-agent immune checkpoint inhibition after surgery reduced the risk of disease recurrence or death in patients with high-risk clear cell renal cell carcinoma (RCC),...
Trials stopped early as benefits shown for olaparib in breast cancer
Women with hereditary breast cancer, triggered by the BRCA1 or BRCA2 genes, stand a better chance of survival following successful trials of a drug...
PARP inhibitor shrinks tumours in pancreatic cancer with mutations
More than two-thirds of pancreatic cancer patients harbouring genetic mutations saw their tumour stop growing or shrink substantially after being switched from intensive chemotherapy...
Sugary drinks associated with increased risk of colorectal cancer in women
Heavy consumption of sugary drinks during adolescence and adulthood is associated with an increased risk of developing colorectal cancer in women under age 50,...
An epidemiological insight into HPV status and prognostic gene mutations in head and neck cancer
A study release from Clarivate:
Summary
Since human papilloma virus (HPV) infection is related to sexual practices and HPV positive head and neck cancers (HNCs), particularly...
Immunotherapy combination shows early promise in glioblastoma
Immunotherapy together with an experimental cancer drug could offer a new way of treating some patients with aggressive brain cancers, promising early results from...
Bariatric surgery significantly cuts cancer risk in severely obese NAFLD patients
Bariatric surgery can significantly reduce the risk of cancer – and especially obesity-related cancers – by as much as half in certain individuals, according...
CT scan catches 70% of lung cancers at early stage — SUMMIT study
Giving smokers and ex-smokers a CT scan uncovers cancerous lung tumours when they are at an early enough stage so they can still be...
MRI improves detection of clinically significant prostate cancer — IP1-PROSTAGRAM study
MRI improved detection of clinically significant prostate cancer without increasing overdiagnosis compared with PSA testing, according to a prospective, population-based, blinded cohort study. The...
Pre-diagnosis aspirin use may lower colorectal cancer mortality — American Cancer Society
A study finds that long-term aspirin use before a diagnosis of colorectal cancer (CRC) may be associated with lower CRC-specific mortality, found an American...
Faecal transplant boosts immunotherapy in advanced melanoma
Researchers at UPMC Hillman Cancer Centre, the University of Pittsburgh School of Medicine, the National Cancer Institute (NCI), Oregon State University and the National...
Earlier-age daily aspirin linked to lower incidence of colorectal cancer in aged
There is substantial evidence that a daily aspirin can reduce risk of colorectal cancer in adults up to age 70. An a large data...
Better post-surgery care would 'dramatically improve' cancer survival — 82-country study
Patients’ chances of survival after cancer surgery is strongly linked with the standard of post-operation hospital care, with patients in low-and lower-middle-income countries were...
Statins may protect the heart from chemotherapy in early breast cancer
Statins may protect women's hearts from damage caused during chemotherapy for early-stage breast cancer, according to a cohort study.
"Two types of cancer medications,...
Many women could safely skip breast cancer chemo — RxPONDER Trial
More women with early-stage breast cancer may safely forgo chemotherapy, suggests an interim analysis that had a median follow-up of five years of the...
UK to trial blood test that detects more than 50 types of cancer
A novel blood test that can detect more than 50 types of cancer, often before symptoms show, is to be trialled by the UK's...
Lorlatinib a potential first-line option for ALK-positive lung cancer patients
Lung cancer patients with a specific genetic alteration lived longer and were protected against metastasis to the brain when treated early with the drug...
Small personalised cancer vaccine clinical trial to expand following promising early results
A clinical trial at the University of Arizona Health Sciences designed to study the safety and effectiveness of a personalised cancer vaccine in combination...
A month's delay in cancer treatment may raise death risk up to 13%
People whose treatment for cancer is delayed by even one month have 6% to 13% higher risk of dying – a risk that keeps...
Two immune therapy studies show promise in advanced cervical cancer
Preliminary results from two independent, phase II clinical trials investigating a new PD-1 (programmed cell death protein 1)-based immune therapy for metastatic cervical cancer...
Colorectal cancer prevention: BMJ evidence review of 80 meta-analyses
An evidence review in The BMJ examines 80 meta-analyses of interventional and observational studies of colorectal cancer (CRC) prevention using medications, vitamins, supplements and...
Tagriso shown to slow spread of EGFR gene mutation brain metastases
AstraZeneca’s top-selling drug Tagrisso has been shown to slow the spread of a certain type of lung cancer to the brain when diagnosed at...
Combining two precision medicines to treat drug-resistant cancers
Launching a dual-pronged attack on tumours using a combination of two precision medicines could treat patients with multiple common cancers, a clinical trial shows....
Use of permanent hair dye and cancer risk
Women who use permanent hair dye products to colour their hair at home do not experience greater risk of most cancers or greater cancer...
Single dose radiotherapy effective in treating breast cancer
A pioneering breast cancer therapy developed by University College London (UCL) clinicians, which requires just one shot of radiotherapy rather than conventional weeks-long treatment,...
Breast screening women in their 40s to save lives – long-term UK study
A 23-year follow-up of a large UK trial found that screening women aged 40-49 led to a substantial and significant 25% reduction in breast...
Higher end of normal blood platelet count may indicate cancer
Blood platelet counts at the higher end of normal suggest a high risk of cancer in men aged 60 or over, and should be...