Tuesday, 28 September, 2021
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Pharmacology

Interstitial cystitis medication may be toxic to the retina

A drug widely prescribed for a bladder condition for decades, now appears to be toxic to the retina, the light sensing tissue at the...

Antidepressants may reduce anxiety more than depressive symptoms

One of the most common antidepressants, sertraline, leads to an early reduction in anxiety symptoms, several weeks before any improvement in depressive symptoms, the...

Commonly used antibiotics may lead to heart problems

Fluoroquinolone antibiotic use is linked with a higher than twofold risk of aortic and mitral regurgitation, risk being highest with current use followed by...

Tramadol associated with significantly greater risk of hypoglycaemia

The opioid tramadol produced a 10-fold greater risk of developing hypoglycaemia than virtually every other opioid, found a US study. Since its approval in 1995,...

Cannabis flower may be an effective mid-level analgesic

Using the largest database of real-time recordings of the effects of common and commercially available cannabis products in the US, researchers at The University...

Statins’ potential to treat MS unrelated to lowering cholesterol

The widely prescribed statin, simvastatin, can medically help patients with secondary progressive multiple sclerosis (SPMS) – for reasons that might be unrelated to the...

Pure Omega 3 reduces risk of total ischaemic events

Taking a high dose of icosapent ethyl – a pure and stable prescription form of the omega-3 fatty acid known as EPA – significantly...

Considerable added benefit for new drug in the prophylaxis of migraine

The German Institute for Quality and Efficiency in Health Care (IQWiG) has found, overall, ndication of a considerable added benefit of erenumab, a new...

Misconceptions over penicillin allergy deprive patients of best treatment

Most patients who report having a penicillin allergy are not really allergic to this highly effective antibiotic, and they may be missing out on...

Little benefit from vitamin D supplements for over 70s

There is little benefit for those over 70 taking higher dose vitamin D supplements to improve their bone strength and reduce the risk of...

Variant of wasp venom to treat bacterial infections

Massachusetts Institute of Technology (MIT) researchers, using toxin found in a South American wasp, have created peptide variants potent against bacteria but nontoxic to...

Alirocumab lowers risk of additional heart attacks or stroke

In a clinical trial involving 18,924 patients from 57 countries who had suffered a recent heart attack or threatened heart attack, researchers found that...

Medical cannabis provides symptom relief for a myriad of complaints

Medical cannabis can provide statistically and clinically significant relief from symptoms from dozens of health conditions with relatively minimal negative side effects, according to...

Taking ayahuasca is like having a near-death experience – study

A psychedelic drug taken as part of the South American plant brew ayahuasca produces effects that are strikingly similar to near-death experiences, a study...

Aspirin with acid reducers helps acid reflux patients slow cancer advance

Taking aspirin with acid reducers can help patients with chronic acid reflux slow the advance of cancer of the oesophagus, the tube from the...

Link found between PPIs and pneumonia in older people

A large University of Exeter analysis has found a statistical link between pneumonia in older people and the use of proton-pump inhibitors (PPIs). Although these...

Newly diagnosed dementia patients 'unnecessarily' over medicated

An international study led by the University of Sydney has found that medication use increases in newly diagnosed dementia patients, particularly unnecessary or inappropriate...

Cape Town Metro clinics ignoring guidelines on antibiotics

Clinics are ignoring guidelines on prescribing antibiotics more than half of the time‚ a study has found. And almost one in five people who...

Acetaminophen over-dose risk rises in the flu season

A study reveals that acetaminophen use and over-dosing rise in cold/flu season in the US, primarily due to increased use of over-the-counter combination medications...

15% of NSAIDs' users exceed maximum recommended dosage

Chances are you or someone you know has used non-steroidal anti-inflammatory drugs (NSAIDs) within the last month. NSAIDs, such as Advil (ibuprofen), Aleve (naproxen)...

Alzheimer's: Benzodiazepine and related drugs raise mortality by 40%

Benzodiazepine and related drug use is associated with a 40% increase in mortality among persons with Alzheimer's disease, according to a study from the...

No causal association between HPTS and birth defects — UK commission

The use of hormonal pregnancy tests (HPT), like Primodos, did not cause birth defects of miscarriages, a UK scientific review has found. The Commission...

Traditional South American drug improving wellbeing

A psychedelic drug traditionally used in South America improves people's general sense of wellbeing and may offer a treatment for alcoholism and depression, new...

Warfarin associated with lower risk of some cancers

Warfarin appeared to be associated with reduced cancer risk in a national European population, found an observational study. Warfarin is a widely used anticoagulant prescribed...

Safety and effectiveness of 4 Alzheimer's drugs ranked

A study ranking the safety and effectiveness of four drugs taken to enhance concentration, memory, alertness and moods, found that donepezil was most likely...

All clear for a trial of Ecstasy drug in PTSD patients

According to a Science Magazine report, the US Food and Drug Administration (FDA) has designated 3.4-methylenedioxymethamphetamine (MDMA), better known as the illegal drug ecstasy,...

Caution urged over 'new frontier' anti-inflammatory that slashes CVD and cancer risk

A pioneering drug, currently used to treat juvenile arthritis, has been found in a trial to also to cut the risk of heart attack...

Debate on long-term psychiatric drug use

The benefits of psychiatric drugs have been exaggerated and the harms underplayed due to poor trial designs, argues one expert. But another expert and a patient contend that the evidence supports the use of these drugs, in a debate on the pages of The British Medical Journal.

Pricey cancer drugs gets rushed approvals despite poor trials

Highly priced cancer drugs get rushed approvals from benign regulatory authorities, despite poor trial methodology and little effect on the longevity of patients, cautions a British-American study. Unlike most other diseases, cancer instils a special fear and 'is treated as an evil, invincible predator, not just a disease', the authors note. Researchers compared 8942 oncology clinical trials conducted between 2007 and 2010 with trials for other diseases. Trials for cancer drugs were 2.8 times more likely not to be randomised, 2.6 times more likely not to use a comparator (single arm), and 1.8 times more likely not to be blinded.

WHO's new essential medicines list

The World Health Organisation has published the new edition of its Model List of Essential Medicines which includes ground-breaking new treatments for hepatitis C, a variety of cancers and multi-drug resistant tuberculosis (TB), among others.

Positive results for dalbavancin

Dalbavancin has potent in vitro activity against staphylococci and streptococci, including isolates with multi-drug-resistant (MDR) phenotypes, according to a study reported at the 25th European Congress of Clinical Microbiology and Infectious Diseases.

Fake medicines pose an urgent risk

The American Journal of Tropical Medicine and Hygiene has released a special supplement on falsified and substandard medicines, most of which articles address the issue of poor quality malaria drugs.