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Fear of side-effects the greatest barrier to long-acting injectable PrEP

Fear of potential severe side effects may be the greatest barrier to long-acting injectable HIV prevention among men who have sex with men (MSM),...

Invitation to participate in Stellenbosch’s online COVID-19 vaccine implementation study

Researchers from the Centre for Medical Ethics and Law (CMEL) at Stellenbosch University are exploring the acceptability and robustness of the electronic consent process...

Predatory medical journals: Finding nuggets among dross

Increasing numbers of studies published by predatory journals are appearing in leading biomedical databases. The challenge in meta-analyses and systematic reviews is to efficiently...

COVID-19 Wuhan lab escape theory gets a second look

Initially dismissed as conspiracy theory, the possibility that the COVID-19 is the consequence of a Chinese laboratory accident is suddenly getting a second look,...

Retraction of study on China's controversial anal-swab COVID-19 test

An article claiming that anal swabs can be used to detect SARS-CoV-2 in patients cured of COVID-19 has been retracted after the journal found...

Brain imaging study paused over LGBTQ+ advocates' concerns

Criticism from LGBTQ+ organisations has put a halt, at least temporarily, to a US National Institute of Health-backed imaging study amid “grave concerns” about what...

SA should have better leveraged its participation in vaccine trials

South African authorities should have in advance leveraged participation in vaccine clinical trials to ensure better post-trial benefits, write Prof Keymanthri Moodley and Prof...

Protecting Africa from becoming a vaccine test lab for the world

Despite the lack of clinical trial and public data on the safety and efficacy of Chinese COVID-19 vaccines, several African countries, including Egypt and...

The challenge of trialling Africa's traditional medicines

As South Africa battled COVID-19 and deaths rose, many turned to traditional herbs for treatment, writes Medscape. The problem is how to bring scientific...

COVID vaccine race dilemma — Ethical or inequitable access?

Some things are bigger than money, and one of them is health, says the Desmond & Leah Tutu Legacy Foundation. In a statement it...

Convalescent plasma flops for severe COVID-19

Researchers in Argentina have found that neither clinical status nor overall mortality was improved in COVID-19 patients with severe pneumonia treated with convalescent plasma...

COVID toll turns spotlight on Europe's taboo on data by race

Many European countries avoid breaking down data along racial or ethnic lines out of concern over privacy or discrimination, but COVID-19ʼs outsized impact on Black...

Women more likely to follow guidelines to prevent spread of COVID-19 — NYU & Yale

Women are more likely than are men to follow guidelines outlined by medical experts to prevent the spread of COVID-19, research finds. New York...

WHO's Ghebreyesus warns on BCG vaccine as global trial starts

The BCG vaccine might result in less severe COVID-19 and more rapid recovery, writes World Health Organisation Director General Dr Tedros Ghebreyesus. But it...

Research imperialism shows need for functioning SA research ethics oversight body

Africa is known for its excellent safaris, with tourists flying from around the world, only to leave ‘with barely a hint’ of having been...

Lack of consideration of sex and gender in clinical trials for COVID-19

An international analysis warns that in the race to develop medical interventions for the coronavirus, scientists have paid scant attention to gender when recruiting...

Black distrust leads to task force to vet US health agencies' decisions

In response to a withering of trust in US health agencies, a group of Black physicians has created their won task force to independently...

British COVID-19 test gives results in 90 minutes with 94% accuracy — Lancet

A 90-minute COVID-19 test has been shown to have over 94% sensitivity, and 100% specificity in a new study. The work was led by...

COVID-19 challenges and strategies — SA academic hospital

Six months after South Africa’s first confirmed case of the deadly COVID-19 virus – which spread across the country and has so far infected...

COVID-19 may damage immune cells in the bone marrow — UK study

Even bone marrow may not be a safe harbour from the ravages of COVID-19, according to a study that found previously unrecognised changes in...

COVID19’s catastrophic effect on drug and treatment clinical trials

More than 1,500 clinical trials of new drugs and treatments for cancers, heart disease and other serious illnesses have been permanently closed down in...

'Heart-breaking' study of endometriosis retracted after 7 years

A widely criticised peer-reviewed study that measured the attractiveness of women with endometriosis has been retracted from the medical journal Fertility and Sterility. The...

A 'glaring' lack of darker skin in textbooks and journals

There has for decades been a glaring lack of representation of black and brown skin in dermatology journals and textbooks, writes STAT News. The...

Assessing antiviral activity of chloroquine and hydroxychloroquine — 2 studies in Nature

Chloroquine and hydroxychloroquine show no notable antiviral effect against infections with SARS-CoV-2 in macaques or human lung cells according to two studies. Hydroxychloroquine and...

Six distinct symptom clusters of COVID-19 identified — King's College London

Analysis of data from the COVID Symptom Study app, led by researchers from King’s College London, reveals that there are six distinct “types” of...

Three distinct immune responses for sicker COVID-19 patients — Penn Institute of Immunology

Researchers from the Penn Institute of Immunology have discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of...

UK herd immunity threshold and seasonal exposure — Oxford epidemiological study

The UK population may already have developed sufficient levels of herd immunity required to prevent a feared second wave of the coronavirus pandemic in...

Drug that calms 'cytokine storm’ linked to 45% lower risk of COVID-19 ventilator deaths

Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45% less likely to die...

No increased COVID-19 mortality for people with HIV — large US cohort analysis

An analysis of the largest cohort of people living with HIV in the US found that they were not more likely to contract the...

COVID-19 pneumonia patients improve with immunosuppressant — Small US observational study

Most patients hospitalised with COVID-19 (coronavirus) pneumonia experienced improvement after receiving a US Food and Drug Administration-approved drug normally given for rheumatoid arthritis, according...

Mask wearing effectiveness, including among asymptomatic COVID-19 carriers

  The two hair stylists in Springfield, Missouri, broke the cardinal rule of infection control: STAT News reports that despite having respiratory symptoms, one went...

Heparin 'potentially blocks' COVID-19 — US laboratory study

A common drug, already approved by the US Food and Drug Administration (FDA), may also be a powerful tool in fighting COVID-19, according to...

SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers

Health-care workers (HCWs) are at high risk of developing COVID-19, and may themselves contribute to transmission. To evaluate these risks, we enrolled 200 patient-facing...

Small study shows treatment reducing odds of COVID-19 disease progression

Experts have cautiously welcomed the results of a small trial of a coronavirus treatment that has dramatically reduced the odds of hospitalised patients progressing...

Almost half of hospitalised COVID-19 patients show heart scan abnormalities — Global study

Almost half of COVID-19 patients who have been hospitalised show scan abnormalities that resemble the early stages of heart failure, a global research study...

Global review of BCG vaccine protection from severe COVID-19

A epidemiological evidence review suggests a negative association between national bacillus Calmette–Guérin (BCG) vaccination policy and the prevalence and mortality of coronavirus disease. However,...

Comprehensive review of COVID-19's extrapulmonary effects

After only a few days caring for critically ill COVID-19 patients at the start of the outbreak in New York City, Dr Aakriti Gupta,...

COVID-19 linked strokes more severe and have worse outcomes — Acute Stroke Registry

Acute ischaemic strokes (AIS) associated with COVID-19 are more severe, lead to worse functional outcomes and are associated with higher mortality, according to researchers...

Neurological complications linked to COVID-19 occurring globally — University of Liverpool review

A review by University of Liverpool researchers has shown that strokes, delirium and other brain complications are reported from most countries where there have...

Blacks at doubled higher risk for COVID-19 — University of Chicago analysis

Results of an analysis has found that Black individuals were twice as likely as White individuals to test positive for COVID-19. The average age...